Lipid composition and Na+,K+-ATPase activity in erythrocyte membranes of patients with type 2 diabetes mellitusand dyslipoproteinemia

Кравец, Е. Б.; Борисовна, Кравец Елена; Stepovaya, E. A.; Алексеевна, Степовая Елена; Koshchevets, Tatiana Yur'evna; Юрьевна, Кощевец Татьяна; Medvedeva, Olesya Dmitrievna; Дмитриевна, Медведева Олеся; Yakovleva, N M; Михайловна, Яковлева Наталья; Yadmaa, O.; Оюунчимэг, Ядмаа; Ananina, E A; Александровна, Ананина Елена

doi:10.14341/2072-0351-6015

Diabetes mellitus

2010

DOI: 10.14341/2072-0351-6015

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Lipid composition and Na+,K+-ATPase activity in erythrocyte membranes of patients with type 2 diabetes mellitusand dyslipoproteinemia

Е. Б. Кравец

Кравец Елена Борисовна²,

E. A. Stepovaya

et al.

Abstract: Aim. To study lipid composition and Na+,K+-Na+,K+-ATPase activity in erythrocyte membranes of patients with type 2 diabetes mellitus and dyslipoproteinemia. Materials and methods. The study included 40 patients (22 men and 18 women) aged 40-65 years with DM2. Results. The patients had abnormal lipid composition and impaired Na+,K+-Na+,K+-ATPase activity in erythrocyte membranes. The magnitude of thesechanges depended on the duration of pathology, severity of diabetic dyslipoproteinemia, and quality of compe… Show more

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2023

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Cited by 2 publications

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The Structure of the Lipid Phase of the Erythrocyte Membrane in Patients With Expressed Hemolysis After Surgery With Cardiopulmonary Bypass

Хохлов

2013

Bûll. sib. med.

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The composition of lipid phase of red-cell membrane in patients with ischemic heart disease (IHD) with pronounced postperfusion hemolysis (18 patients) before coronary artery bypass surgery and 1 hour after the completion of cardia bypass (CB) has been studied. It is shown that patients with IHD with pronounced hemolysis are characterized by the normal ratio of phospholipids (PL) fractions in red-cell membrane before surgery, which is connected with eth high content of young forms of red cells in blood at this stage. After surgery, the fraction of lysophosphatidylcholine and phosphatidic acid in red-cell membrane increases against the background of decrease of phosphatidylinositol and phosphatidylcholine, which likely reflects the simultaneous activation of phospholipases of three classes (A, C, and D) in red cells during CB. Regardless of the phase of the study, the total content of PL in red-cell membrane of IHD patients with pronounced hemolysis is decrease at the high level of cholesterol (CS) and the CS/Pl ratio.

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The Structure of the Lipid Phase of the Erythrocyte Membrane in Patients With Expressed Hemolysis After Surgery With Cardiopulmonary Bypass

Хохлов

2013

Bûll. sib. med.

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Assessment of Motor Activity of Patients Undergoing Medical Rehabilitation and Health Resort Treatment

Fesyun,

Marchenkova,

Vasileva

2023

Bulletin of Rehabilitation Medicine

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INTRODUCTION. Problem of evaluation of the motor activity patients undergoing medical rehabilitation and sanatorium treatment remains relevant, including obesity. AIM. To study the nature and degree of disorders of muscle strength, motor and coordination functions in patients undergoing medical rehabilitation and sanatorium treatment. MATERIALS AND METHODS. Single cross-sectional study included 160 patients aged 40 to 65 years with normal and overweight. The complex of the study included: functional tests and assess muscle strength and balance. RESULTS. In patients with obesity, compared with persons with normal body weight of the same age, significantly (p 0.05) lower indicators of muscle strength of the right and left arms, strength of the abdominal and back muscles, lower endurance of the abdominal muscles and back muscles and longer time to complete the “Get up and walk” test. Also, in obesity, it turned out to be significantly less time to maintain balance in the “Stand on one leg” tests on the right and left legs with open eyes. A statistically significant direct relationship was found between the level of back muscle strength (γ = −0.82, p = 0.0038) and body weight. A significant relationship was also found between the level of endurance of the back muscles to physical activity and BMI (γ = −0.79, p = 0.01). At the same time, there was no relationship between age and the level of endurance of the back muscles to physical activity (γ = 0.107, p = 0.36). DISCUSSION. In patients undergoing medical rehabilitation and health resort treatment, obesity is associated with a decrease in muscle strength and motor activity. CONCLUSION. In patients with obesity at the age of 40–65 years, compared with persons with normal body weight of the same age and gender, there is a statistically significant decrease in the muscle strength of the arms, abdomen and back, a longer time to complete the “Get up” test and walk”, as well as deterioration in the function of static balance according to the results of the “Stand on one leg” test.

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Lipid composition and Na+,K+-ATPase activity in erythrocyte membranes of patients with type 2 diabetes mellitusand dyslipoproteinemia

Cited by 2 publications

References 3 publications

The Structure of the Lipid Phase of the Erythrocyte Membrane in Patients With Expressed Hemolysis After Surgery With Cardiopulmonary Bypass

The Structure of the Lipid Phase of the Erythrocyte Membrane in Patients With Expressed Hemolysis After Surgery With Cardiopulmonary Bypass

Assessment of Motor Activity of Patients Undergoing Medical Rehabilitation and Health Resort Treatment

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