Lipid absorption by silicone heart valve poppets—in‐vivo and in‐vitro results

Carmen, Raleigh; Mutha, S.C.

doi:10.1002/jbm.820060504

Cited by 52 publications

(6 citation statements)

References 2 publications

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“…In addition, the adsorption of adsorbed on PE increased with increasing HDL concentration of a single protein solution until 5 mg/ml, and increasing plasma selected lipid and lipoprotein components on heart valve concentration resulted in an increase of HDL adsorption. In addi-prostheses after implantation in human beings has been retion, HDL adsorption from an HDL solution of 500 mg/ml on PE ported earlier (8,9). A decreased level of HDL has been reached a maximum within a few minutes at 25ЊC.…”

Section: The Adsorption Of Hdl From a Single Protein Solution And Amentioning

confidence: 99%

Adsorption of High Density Lipoproteins (HDL) on Solid Surfaces

Feng

Morales

Beugeling

et al. 1996

Journal of Colloid and Interface Science

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lesterol back to the liver (reverse cholesterol transport (4)) The adsorption of high density lipoproteins (HDL) on polyeth-or transferring cholesterol to very low density lipoproteins ylene (PE), poly(2-hydroxyethyl methacrylate) (poly(HEMA)), (VLDL) or low density lipoproteins (LDL) by the cholepolyesterurethane (PU), Biomer, and mica surfaces was studied. steryl ester exchange protein. The adsorption of HDL from a single protein solution and aAn interesting observation was made in our laboratory plasma solution on the surfaces showed that the amount of ad-(5-7), indicating that HDL preferentially adsorbs on hysorbed HDL was not related to the hydrophobicity (or hydrophilicdrophobic polymer surfaces, resulting in a low adsorption ity) of the surfaces. It was observed that the amount of HDL of fibrinogen from plasma. In addition, the adsorption of adsorbed on PE increased with increasing HDL concentration of a single protein solution until 5 mg/ml, and increasing plasma selected lipid and lipoprotein components on heart valve concentration resulted in an increase of HDL adsorption. In addi-prostheses after implantation in human beings has been retion, HDL adsorption from an HDL solution of 500 mg/ml on PE ported earlier (8,9). A decreased level of HDL has been reached a maximum within a few minutes at 25ЊC. Only a propor-observed in blood plasma of patients undergoing hemodialytion of adsorbed HDL could be desorbed when the adsorbed layers sis (10, 11). However, the adsorption of HDL on various were incubated with Tween 20 or sodium dodecyl sulfate (SDS), solid surfaces has not been studied in detail. A better underwhile the desorption was dependent on the nature of the surfaces.standing of HDL adsorption will probably provide more inIt was more difficult to desorb HDL adsorbed from plasma to PE formation on the blood compatibility of biomaterials and the than to desorb HDL adsorbed from a single protein solution to interpretation of the change of HDL concentration in plasma. PE. It was found that the desorption of adsorbed HDL from PE by the detergents was decreased if the protein layer had beenTo establish whether a protein is adsorbed reversibly, destored in buffer (pH 7.4) for 24 h before desorption, while a higher sorption studies are generally necessary. However, few instoring temperature had a negative effect on the desorption of vestigations have been performed regarding the desorption the lipoprotein from the surface. Adsorbed HDL on mica in a of HDL from solid surfaces (12). Therefore, the desorption physiological buffer was imaged by a tapping mode atomic force of HDL in the presence of detergents was studied to provide microscope (AFM). The surface appeared to be covered by single more information about the stability of adsorbed HDL. De-HDL proteins as well as clusters of two or three HDL proteins spite the numerous experiments conducted so far to study with an average height of 5 to 6 nm. Furthermore, the partial protein adsorption on surfaces, the molecular details of these desorption of adsorbed...

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Section: The Adsorption Of Hdl From a Single Protein Solution And Amentioning

confidence: 99%

Adsorption of High Density Lipoproteins (HDL) on Solid Surfaces

Feng

Morales

Beugeling

et al. 1996

Journal of Colloid and Interface Science

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“…Earlier, it had been postulated that the decrease in implant durability, from that of the in vitro studies, was due to lipid absorption causing molecular weakening. This type of molecular change has been reported in long-term studies involving heart valve failures (9,10). The application of this theory to the flexible joint implant was discounted by a 1973 study indicating an insignificant amount of lipid transfer between the joint fluid and the implant.…”

Section: Vcotmentioning

confidence: 78%

An Animal Model for the Implantation of a Bone Liner in the Flexible Implant Arthroplasty

McGehee¹,

Swanson²,

Braden³

1988

Vet Comp Orthop Traumatol

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A retrospective study of silicone elastomer implants used clinically as a flexible implant in the metacarpophalangeal (MP) and proximal interphalangeal (PIP) joints in humans indicated a 7.6% implant fracture failure rate. Implant fractures appeared to occur from tear propagation due to damage resulting from the impingement of the sharp bone edges upon the implant’s surface. A protective synthetic bone liner was devised to reduce in vivo damage and prevent implant failures. The rabbit stifle was used as the animal model for the human metacarpophalangeal and proximal interphalangeal joint and 73 implant arthroplasties were successfully performed.

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“…PHVs or mechanical heart valves fabricated from synthetic materials ( Table 1) have lifetime durability. However, patients Detmer et al, 1972;Gentle and Juden, 1984;Thornton et al, 1997 Polyurethane urea Jayabalan et al, 2000;Thomas et al, 2001;Thomas and Jayabalan, 2009 Polyurethane (PU) Mackay et al, 1996;Bernacca et al, 1997aBernacca et al, ,b, 2002bWheatley et al, 2000 Polyvinyl alcohol (PVA) Tadavarthy et al, 1975;Wan et al, 2002;Jiang et al, 2004;Millon and Wan, 2006 Silicone Carmen and Kahn, 1968;Carmen and Mutha, 1972;Cuddihy et al, 1976;Parfeev et al, 1983;Black, 1984 Titanium Mitamura et al, 1989;Jones et al, 2000;Aagaard, 2004;Leng et al, 2006;Guldner et al, 2011 Pyrolytic carbon Björk, 1972;Schoen et al, 1982;Goodman et al, 1996;Ritchie, 1996;Ely et al, 1998;Litzler et al, 2007 Polyether urethane (PEU) Boretos et al, 1975;Bernacca et al, 1995Bernacca et al, , 1997aWheatley et al, 2000 Polycarbonate urethane (PCU) Daebritz et al, 2004;Sachweh and Daebritz, 2006;<...>…”

Section: Application Of Biomaterials In Heart Valvesmentioning

confidence: 99%

Biomaterials in Valvular Heart Diseases

Taghizadeh

Ghavami

Derakhshankhah

et al. 2020

Front. Bioeng. Biotechnol.

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Valvular heart disease (VHD) occurs as the result of valvular malfunction, which can greatly reduce patient’s quality of life and if left untreated may lead to death. Different treatment regiments are available for management of this defect, which can be helpful in reducing the symptoms. The global commitment to reduce VHD-related mortality rates has enhanced the need for new therapeutic approaches. During the past decade, development of innovative pharmacological and surgical approaches have dramatically improved the quality of life for VHD patients, yet the search for low cost, more effective, and less invasive approaches is ongoing. The gold standard approach for VHD management is to replace or repair the injured valvular tissue with natural or synthetic biomaterials. Application of these biomaterials for cardiac valve regeneration and repair holds a great promise for treatment of this type of heart disease. The focus of the present review is the current use of different types of biomaterials in treatment of valvular heart diseases.

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Lipid absorption by silicone heart valve poppets—in‐vivo and in‐vitro results

Cited by 52 publications

References 2 publications

Adsorption of High Density Lipoproteins (HDL) on Solid Surfaces

Adsorption of High Density Lipoproteins (HDL) on Solid Surfaces

An Animal Model for the Implantation of a Bone Liner in the Flexible Implant Arthroplasty

Biomaterials in Valvular Heart Diseases

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