Lipedematous scalp and lipedematous alopecia: A clinical and histologic analysis of 3 cases

Çocukta obezite ile birlikte lipoödematöz skalp

“…The histopathological changes include dilated dermal lymphatic vessels, usually normal epidermis, increased thickness of the subcutaneous adipose tissue and dermal edema (2). In our patient, we found elastic fragmentation, coarse collagen bundles and mild perivascular mononuclear cell infiltration in superficial dermis, increased subcutaneous fat tissue with hair follicles and normal dermis.…”

“…The exact etiology is unknown, but the characteristic finding is increscent in scalp thickness due to expansion of subcutaneous adipose tissue in the absence of adipose tissue hypertrophy or hyperplasia (1). If there were accompanying hair loss, the condition would have been called lipedematous alopecia (LA) (2). Both of them have been reported mostly in black women in the literature (1,3).…”

Lipedematous scalp in a patient with ankylosing spondylitis

“…There is no clear association between lipedematous scalp and a specific medical disorder and its pathogenesis remains unclear [2,5]. There is ongoing debate involving hormonal factors, since most of the reported cases occurred in women and is proposed an association with obesity [3,5,6].…”

“…This entity of unknown etiology is described as thickening of the scalp subcutaneous tissue without capillary changes, usually accompanied by local pain and less commonly by paresthesia and pruritus [2]. The lipedematous alopecia is a similar disease associated with varying degrees of hair loss and/or inability to maintain hair growth above 2 cm, although there is no consensus if they can be spectra of the same disease [3,4].…”

Spontaneous Resolution of Lipedematous Scalp after 13 Years

“…On the contrary, Jone et al [11], suggested adipose metaplasia and developmental displacement of adipose tissue or possible origin of adipocytes from the wall of dermal vessels in the course of degenerative changes in dermal connective tissue as recently reported an association of LA with discoid lupus erythematosus has been proposed [11,12]. Regarding the associated alopecia, Martin et al postulated the presence of lymphangiectasia may be responsible for hair loss because it is found only in those patients with lipedematous scalp and alopecia [13]. Others relate alopecia to compression of the superficial blood capillaries by the increased volume of the subcutaneous fat layer within the thickened scalp.…”