Lipase-Catalyzed Synthesis of Butyl Butyrate by Alcoholysis in an Integrated Liquid-Vapor System

Paiva, Ana L.; Rossum, Diman van; Malcata, F. Xavier

doi:10.1021/bp0201298

Cited by 22 publications

(24 citation statements)

References 8 publications

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“…Lipases (triacyl glycerol hydrolases, E.C. 3.1.1.3) are used to breakdown fats, triglycerides, and can be used for esterification and transesterification in organic solvents,3–20 in supercritical fluids21–31 and solvent free condition 32–34. Lipase are more stable at higher pressures,35 some studies have shown surfactant‐coated lipase,3 lipase encapsulated in silica aerogels4, 5 and lipase encapsulated in microemulsion‐based organogels give better activity and, therefore, can be used more effectively for esterification and transesterification.…”

Section: Introductionmentioning

confidence: 99%

“…The kinetics of esterification to butyl isobutyrate6 was reported in heptane ignoring the kinetics of hydrolysis. Some studies have reported the integrated liquid–vapor32 and solid–liquid–vapor33 system for synthesis. Santos et al 7 used factorial design to optimize the lipase catalyzed synthesis of butyl butyrate in heptane, while Lozano et al 9 studied the continuous synthesis of butyl butyrate using an active membrane coated with lipase.…”

Section: Introductionmentioning

confidence: 99%

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Development and application of triglyceride‐based polymers and composites

Khot

LaScala

Can

et al. 2001

J of Applied Polymer Sci

602

505

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Micromechanical deformation processes responsible for toughening mechanisms in ultrafine monospherical inorganic particle-filled polyethylene were investigated in situ by a field-emission gun-environmental scanning electron microscope (FEG-ESEM) with low-voltage techniques. In general, the ultimate properties of polymer composites are largely dependent on the degree of dispersion of filler particles into the matrix. Very often, the agglomeration is one of inevitable occurrences in polymer composites, mixed with ultrafine filler particles. In the present work, the effects of agglomerates, consisting of ultrafine monospherical filler particles, were reexamined in polymer composites on the toughening mechanism. The results show that the dominant micromechanical deformation processes are the multiple debonding processes inside agglomerates, in which the ratio of the matrix strand and the size of agglomerate plays a great role of matrix yielding. In the specimen, where the agglomerates are isolated in the matrix, deformation begins at the equatorial region of agglomerates and propagates through them. However, in the case of closely placed agglomerates, deformation occurs homogeneously within the whole area inside the agglomerates. In both cases, in conjunction with the multiple debonding processes, the major part of energy during the deformation dissipates through the shear-flow processes of the matrix material. In particular, the micromechanical deformation processes observed in this work confirm that the agglomerates do not always have negative effects on the mechanical properties-at least, in the shear deformable semicrystalline polymer matrices. The agglomerates may be effectively used for the improvement of toughness. Furthermore, the FEG-ESEM with low-voltage techniques offers an extremely promising and efficient alternative method to study the morphology as well as in situ micromechanical deformation processes in nonconducting polymer systems.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Development and application of triglyceride‐based polymers and composites

Khot

LaScala

Can

et al. 2001

J of Applied Polymer Sci

602

505

View full text Add to dashboard Cite

show abstract

“…The kinetics of esterification to butyl isobutyrate 6 was reported in heptane ignoring the kinetics of hydrolysis. Some studies have reported the integrated liquid-vapor 32 and solid-liquid-vapor 33 system for synthesis. Santos et al 7 used factorial design to optimize the lipase catalyzed synthesis of butyl butyrate in heptane, while Lozano et al 9 studied the continuous synthesis of butyl butyrate using an active membrane coated with lipase.…”

Section: Introductionmentioning

confidence: 99%

Kinetics of synthesis of butyl butyrate by esterification and transesterification in supercritical carbon dioxide

Varma

Madras

2008

J of Chemical Tech & Biotech

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“…Further advantages such as overcoming equilibrium limitations, achieving higher selectivity, reducing catalyst requirement, easier separation of azeotropic mixtures, avoidance of hot spot or use of reaction heat for the distillation have resulted in significant interest in RD as an alternative process for the chemical industry and academia, in recent years [1][2][3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Predictions for Start‐Up Processes of Reactive Distillation Column via Artificial Neural Network

Tang

et al. 2006

Chem Eng & Technol

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The time consumed in starting up the unit with appropriate holdups can form an important part of the total distillation time, particularly for reactive distillation systems with large holdups. Also, the products formed during the start-up time are off specification, and are not easily recycled as for traditional distillation, but must be carefully disposed of, which can be very costly. A back-propagation algorithm artificial neural network model is presented as a tool to assess the start-up process for a given reactive distillation system. All the data required for training and testing the artificial neural network have been generated using the CHEMCAD simulator, version 5.2-0. The values for the learning rate, momentum term, and gain term of the artificial neural network have been taken as 0.01, 0.6, and 1.0, respectively. From the case studied in this work, it can be seen that a good start-up policy can reduce both the energy and time requirements in the start-up phase of reactive distillation processes. Results from predictions show the time consumed in the start-up period has an average error of 2.833 %, and a maximum error of 7.600 %, for the case studied here. The accuracy of the model will depend upon the data available and the type of model being approximated.

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Lipase-Catalyzed Synthesis of Butyl Butyrate by Alcoholysis in an Integrated Liquid-Vapor System

Cited by 22 publications

References 8 publications

Development and application of triglyceride‐based polymers and composites

Development and application of triglyceride‐based polymers and composites

Kinetics of synthesis of butyl butyrate by esterification and transesterification in supercritical carbon dioxide

Predictions for Start‐Up Processes of Reactive Distillation Column via Artificial Neural Network

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