Lipase‐Catalyzed Asymmetric Synthesis of Desprenyl‐carquinostatin A (V) and Descycloavandulyl‐lavanduquinocin.

Abstract

Alkaloids U 0600Lipase-Catalyzed Asymmetric Synthesis of Desprenyl-carquinostatin A (V) and Descycloavandulyl-lavanduquinocin. -The synthesis of the functionalized carbazole core includes lipase-catalyzed enantioselective esterification as the key step. -(CHOSHI, T.; UCHIDA, Y.; KUBOTA, Y.; NOBUHIRO, J.; TAKESHITA, M.; HATANO, T.; HIBINO*, S.; Chem. Pharm. Bull. 55 (2007) 7, 1060-1064; Fac. Pharm. Pharm. Sci., Fukuyama Univ., Fukuyama, Hiroshima 729-02, Japan; Eng.) -M. Bohle 51-206