Abstract:Artificial neural networks (ANNs) analysis was carried out to optimize the esterification of galanthamine and acetic acid in a solvent system. To predict performance parameters of the enzymatic reaction conditions, several parameters were studied which were reaction temperature (50-90 °C), enzyme amount (2-5 wt%), reaction time (6-18 h), and substrate molar ratio of galanthamine to acetic acid (2-5:1). The algoritms used in the network were batch back propagation (BBP), incremental back propagation (IBP), gene… Show more
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