Linking pollution and cancer in aquatic environments: A review

Ciara, Baines,; Lerebours, Adélaïde; Thomas, Fréderic; Fort, Jérôme; Kreitsberg, Randel; Gentès, Sophie; Meitern, Richard; Saks, Lauri; Újvári, Beáta; Giraudeau, Mathieu; Sepp, Tuul

doi:10.1016/j.envint.2021.106391

Cited by 61 publications

(36 citation statements)

References 193 publications

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“…The positive effect of turbidity on photolysis (by means of increasing diffusion of light through water) contributes to purification in wetlands, which was recognised long ago. Wildlife switching to human food items alters food webs and can promote unnatural growth, but may also alter behaviour and promote disease in animals [ 33 , 34 ].…”

Section: The Urban River Syndrome—ecosystems Previously Transformedmentioning

confidence: 99%

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The Urban River Syndrome: Achieving Sustainability Against a Backdrop of Accelerating Change

Richardson

Soloviev

2021

IJERPH

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Human activities have been affecting rivers and other natural systems for millennia. Anthropogenic changes to rivers over the last few centuries led to the accelerating state of decline of coastal and estuarine regions globally. Urban rivers are parts of larger catchment ecosystems, which in turn form parts of wider nested, interconnected systems. Accurate modelling of urban rivers may not be possible because of the complex multisystem interactions operating concurrently and over different spatial and temporal scales. This paper overviews urban river syndrome, the accelerating deterioration of urban river ecology, and outlines growing conservation challenges of river restoration projects. This paper also reviews the river Thames, which is a typical urban river that suffers from growing anthropogenic effects and thus represents all urban rivers of similar type. A particular emphasis is made on ecosystem adaptation, widespread extinctions and the proliferation of non-native species in the urban Thames. This research emphasizes the need for a holistic systems approach to urban river restoration.

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Section: The Urban River Syndrome—ecosystems Previously Transformedmentioning

confidence: 99%

“…A sometimes overlooked aspect of change is the increase of cancers in animals [ 34 , 92 ]. Heavy metals and other xenobiotics, including those released by plastics following ingestion, can induce cancer.…”

Section: The Urban River Syndrome—ecosystems Previously Transformedmentioning

confidence: 99%

The Urban River Syndrome: Achieving Sustainability Against a Backdrop of Accelerating Change

Richardson

Soloviev

2021

IJERPH

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“…Most of these hazardous chemicals accumulate in various trophic levels of organisms living in aquatic areas. (Bolognesi et al, 1996;Lee et al, 2020;Qin et al, 2020;Baines et al, 2021). They have significant influences in cell damage creating necrosis and neoplasia (Bebianno & Garcia da Fonseca, 2020;Medda et al, 2021), DNA damage (Yaqin, 2006;Asllani et al, 2019;Bolognesi et al, 2019;Pellegri et al, 2020;Guimarães et al, 2021;Camargo Filho et al, 2022), embryonic mortality and mutation (McLaughlin et al, 2020;Ganaie, 2021) and Darwinian fitness such as decrease of growth rates, reproductive output, and viability of offspring (Depledge, 2020).…”

Section: Introductionmentioning

confidence: 99%

“…Molecular biomarkers have been regarded as early warning systems along with the recognized correlation between the genotoxic burden of aquatic ecosystems and carcinogenic effects in humans and wildlife in an epidemic study (Black & Baumann, 1991;Baines et al, 2021;Jeddi et al, 2021;Liu et al, 2022). Besides, the molecular biomarkers, for instance, DNA damage, serve as a good and useful early warning system of carcinogens on different organisms (Kumari & Khare, 2018;Lionetto et al, 2019;Ben Ameur et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

DNA damage and shell malformation in Blue Mussel, <i>Mytilus edulis</i>

Yaqin

2022

Akuatikisle: J. Aqua. Coast. & Isle

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Pollutants in waters that cause DNA damage, such as tributyltin, have been known to cause malformations in the mussel shell, which need attention to be studied. Shell malformations or deformities of blue mussels were observed in Norsminde Fjord harbour. The mean shell thickness index of blue mussels from the polluted site was greater than it from expected clean waters. DNA damages detected using the versatile comet assay which expressed as tail length and olive tail moment were evaluated in blue mussels gill cells both in situ and in vitro. The results showed that the average of DNA damages in treatments, namely the polluted site, tributyltin chloride (TBTC) (10 g/l), and hydrogen peroxide (H2O2) (10 M) were different from the expected unpolluted site. Although comet assay is considered as an unspecific assay, the results proposed the similarity of DNA damage character of blue mussel gill cells when exposed to tributyltin chloride and taken directly from the polluted site. The data obtained are important for assessing the environmental risks created by genotoxic agents, e.g. tributyltin, used as antifouling agents in marine paints.

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“…However, little attention has been paid to the role of human‐induced cancers in infectious diseases’ emergence and spread. Human activities elevate cancer incidences for wildlife species (via chemical pollution, changes in diet, and reductions in genetic diversity; Baines et al, 2021 ; Giraudeau et al, 2018 ; Sepp et al, 2019 ; Ujvari et al, 2018 ). As in humans, cancer burdens generate a range of immunosuppressive disorders in livestock, and likely in wildlife (Pollock & Roth, 1989 ; Vittecoq et al, 2013 ).…”

Section: Introductionmentioning

confidence: 99%

On the need for integrating cancer into the One Health perspective

Dujon

Brown

Destoumieux-Garzón

et al. 2021

Evolutionary Applications

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Summary Recent pandemics have highlighted the urgency to connect disciplines studying animal, human, and environment health, that is, the “One Health” concept. The One Health approach takes a holistic view of health, but it has largely focused on zoonotic diseases while not addressing oncogenic processes. We argue that cancers should be an additional key focus in the One Health approach based on three factors that add to the well‐documented impact of humans on the natural environment and its implications on cancer emergence. First, human activities are oncogenic to other animals, exacerbating the dynamics of oncogenesis, causing immunosuppressive disorders in wildlife with effects on host–pathogen interactions, and eventually facilitating pathogen spillovers. Second, the emergence of transmissible cancers in animal species (including humans) has the potential to accelerate biodiversity loss across ecosystems and to become pandemic. It is crucial to understand why, how, and when transmissible cancers emerge and spread. Third, translating knowledge of tumor suppressor mechanisms found across the Animal Kingdom to human health offers novel insights into cancer prevention and treatment strategies.

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Linking pollution and cancer in aquatic environments: A review

Cited by 61 publications

References 193 publications

The Urban River Syndrome: Achieving Sustainability Against a Backdrop of Accelerating Change

The Urban River Syndrome: Achieving Sustainability Against a Backdrop of Accelerating Change

DNA damage and shell malformation in Blue Mussel, <i>Mytilus edulis</i>

On the need for integrating cancer into the One Health perspective

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