Linkage of viability genes to marker loci in selfing organisms

Hedrick, Philip W.; Muona, Outi

doi:10.1038/hdy.1990.8

Cited by 47 publications

(48 citation statements)

References 10 publications

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“…In a study of transmission ratio distortion with selfing in A. lyrata, some loci did show significant deviations from the expected ratio (Kärkkäi-nen et al, 1999). If both parents carry a given microsatellite allele linked to a deleterious recessive allele, this may result in a deviation from Mendelian expectations at both allele and genotype level (Hedrick and Muona, 1990). There is an indication that this is not the case in our results.…”

Section: Intrapopulation Crossescontrasting

confidence: 54%

Transmission ratio distortion in Arabidopsis lyrata: effects of population divergence and the S-locus

et al. 2007

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We investigated transmission ratio distortion within an Icelandic population of Arabidopsis lyrata using 16 molecular markers unlinked to the S-locus. Transmission ratio distortion was found more often than expected by chance at the gametic level, but not at the genotypic or zygotic level. The gametic effect may be due to meiotic drive or selection acting postmeiotically. At the gametic level, 10.9% of the tests were significant, which is substantially lower than earlier observed in an interpopulation cross (allowing for differences in power)-suggesting that the high level of transmission ratio distortion in the interpopulation cross is due to population divergence. It is also substantially lower than previously observed in intrapopulation crosses at the self-incompatibility locus, suggesting inherent fitness differences of the selfincompatibility alleles. We discuss the possible role of deleterious alleles accumulating at loci under balancing selection. Zygotic effects play a larger role in the interpopulation cross than in the intrapopulation crosses suggesting that Dobzhansky-Muller incompatibilities may be accumulating between the widely diverged populations.

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Section: Intrapopulation Crossescontrasting

confidence: 54%

Transmission ratio distortion in Arabidopsis lyrata: effects of population divergence and the S-locus

et al. 2007

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“…Hedrick & Muona, 1990). Several empirical data sets suggest that fitness does indeed continue to decline with consecutive generations of selfing, at least in some organisms.…”

Section: Discussionmentioning

confidence: 99%

Models for the evolution of selfing under alternative modes of inheritance

Latta

Ritland

1993

Heredity

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In an approach that explicitly incorporates genetic changes over consecutive generations of selffertilization, we contrast the effect of different modes of inheritance for selfing rate upon the evolutionary equilibrium selfing rate. A monotonic decline of fitness with consecutive generations of selfing was assumed. We found the range of conditions permitting evolutionarily stable mixedmating systems to increase with the number of genes controlling the selfing rate. When the mating system is controlled by a single locus with alternative alleles for complete selfing or outcrossing, alleles for selfing concentrate in inbred individuals and are exposed to stronger selection than the average inbreeding depression. By contrast, when alleles of small effect control the selfing rate, selfing rates do not vary as much between inbred vs. outcrossed individuals; this results in the broader stability of mixed mating. We also find that, provided selfing is not caused by recessive alleles, low levels of outcrossing can be maintained when the average relative fitness of selfed progeny is above 0.5. This is postulated to be due to a long-term advantage for occasional outcrossing in terms of the restoration of low inbreeding coefficients. The assumption of a monotonic decline in fitness with consecutive generations of selfing is also discussed.

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“…Such loci can be mapped based on aberrant segregation ratios (e.g. Hedrick & Muona, 1990), but little is known about their function. Our approach is based on slightly modifying the basic models of Bramlett & Popham (1971), Koski (1971), and Lindgren (1975).…”

Section: Introductionmentioning

confidence: 99%

Estimating numbers of embryonic lethals in conifers

1992

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Conifers have recessive lethal genes that eliminate most selfed embryos during seed development. It has been estimated that Scots pine has, on average, nine recessive lethals which act during seed development. Such high numbers are not consistent with the level of outcrossing, about 0.9-0.95, which has been observed in natural populations. Correcting for environmental mortality or using partial selfings provides significantly lower estimates of lethals. A similar discordance with numbers of lethals and observed outcrossing rates is true for other species.

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Linkage of viability genes to marker loci in selfing organisms

Cited by 47 publications

References 10 publications

Transmission ratio distortion in Arabidopsis lyrata: effects of population divergence and the S-locus

Transmission ratio distortion in Arabidopsis lyrata: effects of population divergence and the S-locus

Models for the evolution of selfing under alternative modes of inheritance

Estimating numbers of embryonic lethals in conifers

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