Linkage between the porcine genes encoding immunoglobulin heavy‐chain allotypes and some serum α‐protease inhibitors: a conserved linkage in pig, mouse and human

Juneja, Rajnish; Gahne, B.; Rapacz, J.; Hasler‐Rapacz, Judith

doi:10.1111/j.1365-2052.1986.tb03194.x

Cited by 20 publications

(4 citation statements)

References 21 publications

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“…Ollivier and Sellier (1982), Davies et al (1988) Förster et al ( 1980, Gellin et al ( 1980), Leong et al ( 1983b) Imlah (1965. Andresen ( 1966b), Hesselholt andNielsen (1966) Yerle et al ( 1986), Yerle and Gellin ( 1989) Graphodatsky (1991) Rapacz and Hasler Rapacz ( 1982), Juneja et al ( 1986) Rapacz andHasler Rapacz ( 1982). Juneja et al ( 1986) Rapacz andHasler Rapacz ( 1982), Juneja et al ( 1986) Rapacz andHasler Rapacz ( 1982 Gellin et al (1980Gellin et al ( .…”

Section: Eaj (J) Eac (C) (Chr 7) L Ix Eas (S) Gpl Hal Eah (H)unclassified

“…(1988). Thomson et al (1991) Andresen (1968), Juneja et al (1986) Andresen and Baker ( 1964). Hruban et al ( 1976).…”

Section: Eaj (J) Eac (C) (Chr 7) L Ix Eas (S) Gpl Hal Eah (H)mentioning

confidence: 99%

“…Försterand Hecht (1984, Christensen et al (1985), Dolf and Stranzinger (1986) Junejaand Gähne (1981). Gähne andJuneja (1982.1985), Juneja et al (1986). Van de Weghe et al (1987, Vogeli et al (1987.…”

Section: Eaj (J) Eac (C) (Chr 7) L Ix Eas (S) Gpl Hal Eah (H)mentioning

confidence: 99%

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The gene map of the pig (<i>Sus scrofa domestica</i> L.): a review

Echard

Milan²,

Yerle³

et al. 1992

Cytogenet Genome Res

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Section: Eaj (J) Eac (C) (Chr 7) L Ix Eas (S) Gpl Hal Eah (H)unclassified

“…(1988). Thomson et al (1991) Andresen (1968), Juneja et al (1986) Andresen and Baker ( 1964). Hruban et al ( 1976).…”

Section: Eaj (J) Eac (C) (Chr 7) L Ix Eas (S) Gpl Hal Eah (H)mentioning

confidence: 99%

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The gene map of the pig (<i>Sus scrofa domestica</i> L.): a review

Echard

Milan²,

Yerle³

et al. 1992

Cytogenet Genome Res

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“…It has also been shown that a locus for pig immunoglobulin heavy chain allotypes (Ighl) is located in the a-protease inhibitor linkage group in a terminal position, following Pi2, with a recombination frequency of 8% or 1520% (Vogeli et al 1987). As IGH allotypes are genetically controlled by four tightly linked loci, Ighl, Igh2, Igh3 and Igh4 (see Juneja et al 1986), the linkage group involves also the Igh gene cluster.…”

Section: Discussionmentioning

confidence: 99%

Polymorphism of pig serum α‐protease inhibitor‐3 (PI3) and assignment of the locus to the Pi1, Po1A, Po1B, Pi2, Igh linkage group

et al. 1990

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Polymorphism of an alpha-protease inhibitor, PI3, in pig serum samples was detected using 2D agarose gel (pH 5.4)--polyacrylamide gel (pH 9.0) electrophoresis. Evidence was obtained that the five variants observed (A, B1, B2, C and D) are under genetic control by codominant alleles (Pi3A, Pi3B1, Pi3B2, Pi3C and Pi3D) at one autosomal locus. Variants A, B1, B2 and C inhibited chymotrypsin; there was no appreciable inhibition of trypsin and papain. Variant D did not inhibit chymotrypsin, and therefore its classification as a PI3 variant was put in question. PI3 typing was not possible in about 50% of the studied pigs since in those cases the PI3 variants were either too weak or absent. On the basis of backcross matings and haplotyping in complete families for protease inhibitor loci Pi1, Po1A, Pi2 and Pi3 it was proved that the Pi3 locus belongs to the protease inhibitor gene cluster, and the position of the locus in the linkage group was proposed as being Pi1-Po1A-(Po1B)-Pi3-Pi2-(Igh1, Igh2, Igh3, Igh4).

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Genetic polymorphism of human plasma ?1-B-glycoprotein: phenotyping by immunoblotting or by a simple method of 2-D electrophoresis

1987

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Genetic polymorphism of human plasma (serum) alpha 1B-glycoprotein (alpha 1B) was observed using one-dimensional horizontal polyacrylamide gel electrophoresis (PAGE) pH 9.0 of plasma samples followed by Western blotting with specific antiserum to alpha 1B. A simple method of two-dimensional agarose gel electrophoresis (pH 5.4)-horizontal PAGE (pH 9.0) of plasma samples, followed by general protein staining, was reported as an alternative method for alpha 1B typing. The three different phenotypes of alpha 1B observed (designated 1-1, 1-2, and 2-2) were apparently identical to those reported by Altland et al. (1983), who used double one-dimensional electrophoresis. Family data supported the hypothesis that the three alpha 1B phenotypes are determined by two codominant alleles at an autosomal locus, designated A1B. Allele frequencies in a Swedish population were: A1B1, 0.937; A1B2, 0.063; PIC, 0.111. For clues on linkage relationships of human A1B, the previously known linkages of A1B in pigs and horses, including the one between A1B and the gene that determines susceptibility to malignant hyperthermia in pigs were discussed.

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Linkage between the porcine genes encoding immunoglobulin heavy‐chain allotypes and some serum α‐protease inhibitors: a conserved linkage in pig, mouse and human

Cited by 20 publications

References 21 publications

The gene map of the pig (<i>Sus scrofa domestica</i> L.): a review

The gene map of the pig (<i>Sus scrofa domestica</i> L.): a review

Polymorphism of pig serum α‐protease inhibitor‐3 (PI3) and assignment of the locus to the Pi1, Po1A, Po1B, Pi2, Igh linkage group

Genetic polymorphism of human plasma ?1-B-glycoprotein: phenotyping by immunoblotting or by a simple method of 2-D electrophoresis

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