Lingual thyroglossal duct cysts—A review

Sameer, K.S. Muhammed; Mohanty, Sriloy; Correa, Marjorie; Das, Kanishka

doi:10.1016/j.ijporl.2011.11.025

Cited by 55 publications

(37 citation statements)

References 14 publications

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“…10 However, identification with laryngoscope is not always possible. In addition, as in this case, preceding symptoms may be subtle and non-specific, including dysphonia 7 or mild feeding difficulties. 11 If unidentified, the presence of a lingual thyroglossal duct cyst causing upper airway obstruction may be associated with significant risk for mortality.…”

Section: Discussionmentioning

confidence: 80%

“…This lesion is an uncommon congenital anomaly, comprising only 0.6-3% of thyroglossal duct remnants, which occur in 700 of 10,000 births. 7 Lingual cystic remnants of the thyroglossal duct result from canalization of an epithelial remnant that connects the migrating thyroid gland to the foramen cecum of the tongue, leading to subsequent mucous production and resulting cyst formation. 8 Though rare, these anomalies may cause fixed or dynamic upper airway obstruction by a ball-valve mechanism between the cyst and the laryngeal inlet.…”

Section: Discussionmentioning

confidence: 99%

“…However, prior to surgical intervention, one must confirm normal placement and functioning of thyroid tissue given the possibility of lingual thyroid presenting similarly on cross-sectional imaging. 7 …”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Acute Upper-Airway Obstruction by a Lingual Thyroglossal Duct Cyst and Implications for Advanced Airway Management

Zimmerman¹,

Hupp²,

Bourguet-Vincent³

et al. 2013

Respir Care

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Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Acute Upper-Airway Obstruction by a Lingual Thyroglossal Duct Cyst and Implications for Advanced Airway Management

Zimmerman¹,

Hupp²,

Bourguet-Vincent³

et al. 2013

Respir Care

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“…During the process of primitive thyroid gland descent and expansion, it remains connected to the foregut by means of the thyroglossal duct [1]. Alterations in the process of duct involution and/or thyroid migration can result in the formation of TGDCs and other variant structures including lingual thyroid glands, pyramidal thyroid lobes, and ectopic thyroid glandular tissue [18].…”

Section: Discussionmentioning

confidence: 99%

Can Medullary Thyroid Carcinoma Arise in Thyroglossal Duct Cysts? A Search for Parafollicular C-cells in 41 Resected Cases

Stein

Murugan

et al. 2017

Head and Neck Pathol

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Thyroglossal duct cysts (TGDCs) are present in ~7% of adults and develop from the midline migratory tract between the foramen cecum and anatomic location of the thyroid. Thyroid tissue can be identified in 2/3 of TGDCs, and up to 1% develop associated malignancy, 90% of which are papillary thyroid carcinoma. Cases of follicular and anaplastic carcinoma have been documented, but there are no reports of medullary thyroid carcinoma arising in a TGDC. This is presumably due to the distinct embryologic origin of parafollicular C-cells, from which medullary carcinoma arises. The goal of this study is to determine whether parafollicular C-cells are present in TGDCs. H&E sections from 41 TGDC cases were examined for thyroid tissue, thyroglossal duct remnants, ultimobranchial remnants, and parafollicular C-cells. Immunohistochemistry was performed for TTF-1 and calcitonin. Eighty three percent (34/41) of cases contained thyroid tissue on H&E and by TTF-1. No cases (0/41) had ultimobranchial remnants or parafollicular C-cells on H&E or with calcitonin. One case of papillary carcinoma in a TGDC was identified. These cases illustrate that although TGDCs often contain thyroid tissue, parafollicular C-cells are absent. Therefore, unlike other thyroid neoplasms, there is no evidence to support the possibility of medullary carcinoma arising in a TGDC.

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“…In this group we consider: cysts related to the lymphatic tissue (cystic hygroma and lymphoepithelial cysts), and thyroglossal duct cyst (108)(109)(110).…”

Section: Soft Tissue Non-odontogenic Cystsmentioning

confidence: 99%

Cysts and Pseudocysts of the Oral Cavity: Revision of the Literature and a New Proposed Classification

Menditti¹,

Laino²,

Domenico³

et al. 2018

In Vivo

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This article includes a comprehensive and up-to-date review on the cysts of the oral cavity. Several classifications of odontogenic (OC) and non-odontogenic (non-OC) oral cysts and the surrounding regions have been proposed. We suggest a new critical classification based on an established relationship between anatomical area, histological origin and clinical behavior (frequency, rate of recurrence, malignant potential). Moreover, the differential cytokeratin (CKs) expression of the various cysts is reported as epithelium-specific markers of differential diagnosis. Finally, issues related to differential diagnosis and therapeutic approaches of the cysts included in the two groups are described.

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Lingual thyroglossal duct cysts—A review

Cited by 55 publications

References 14 publications

Acute Upper-Airway Obstruction by a Lingual Thyroglossal Duct Cyst and Implications for Advanced Airway Management

Acute Upper-Airway Obstruction by a Lingual Thyroglossal Duct Cyst and Implications for Advanced Airway Management

Can Medullary Thyroid Carcinoma Arise in Thyroglossal Duct Cysts? A Search for Parafollicular C-cells in 41 Resected Cases

Cysts and Pseudocysts of the Oral Cavity: Revision of the Literature and a New Proposed Classification

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