Lingual alveolar soft part sarcoma; 14 cases: novel clinical and morphological observations

Abstract

Lingual ASPS is a tumour of childhood with a distinctive, predominantly solid growth pattern. Despite typical vascular invasion, the early diagnosis and small tumour size may explain its relatively good outcome.

Alveolar soft part sarcoma of tongue base — A rare presentation of a rare tumor

“…Metastases of this tumor can occur more than ten years after primary tumor removal & radiation. This makes evaluation of the curative treatment & prognosis of ASPS extremely diffi cult [9].…”

“…KTP/532 laser has become an ideal solution to deal with such well circumscribed vascular tumors of the oropharynx [9,10]. Massive bleeding during surgical resection of ASPS has been reported and when located posteriorly in the tongue may be diffi cult to control at surgery.…”

“…Chemotherapy is reserved for pulmonary metastasis. Prognosis is guarded, as 5-year and 20-year survival rates are reported to be 59% and 15%, respectively, with local recurrence and distant metastasis primarily responsible for the poor prognosis of this neoplasm [5,7,9].…”

“…Preoperative embolization for ASPS is useful to control blood loss and the need for transfusion therapy. Aggressive surgical excision is recommended, because local recurrence is common [9,10]. The role of post-operative radiotherapy has remained limited.…”

Clavicular and meningeal alveolar soft part sarcoma: An unusual case and literature review

“…2 In children and infants, ASPS has an unusual tendency to involve the tongue and orbit. 3,4 ASPS rarely occurs in other locations, such as the female genital tract, 5 mediastinum, 6 lung, 7,8 gastrointestinal tract, 9 and bone. 10 Primary bone involvement is rare, and characteristically involves the fibula, ilium and tibia.…”