Linfoma primário de cavidade pleural em paciente imunocompetente

Abstract

Primary effusion lymphoma (PEL) is classified as a non-Hodgkin's lymphoma and is identified as a unique clinical and pathological entity according to the World Health Organization classification system.(1) It is characterized by the presence of cavity effusion, the absence of nodal or extranodal involvement and the incorporation of genetic material (from human herpes virus type ABSTRACTPrimary effusion lymphoma is an unusual non-Hodgkin's lymphoma rarely seen in immunocompetent patients. Herein, we present clinical and biochemical data obtained from an immunocompetent patient diagnosed with primary effusion lymphoma.

Primary effusion lymphoma in women with acquired immunodeficiency syndrome (AIDS), pleural effusion, and ascites: cytological diagnosis and immunocytochemistry

“…Positivity for lymphocyte activation markers (CD30, CD38, CD71, and epithelial membrane antigen) is generally observed in addition to plasma cell differentiation (CD138) and B lymphocyte late stage differentiation (MUM1). 15 The definitive diagnosis is achieved by detecting the infection with HHV-8 in tumor cells based on the nuclear antigen expression associated with the latency (LANA-1) revealed by immunocytochemistry 16 and clonal rearrangements of immunoglobulin genes in molecular studies that indicate the origin in the B lymphocyte post-germinal center.…”