Cutaneous lymphomas are classified according to their cellular origin into T-cell
lymphoma and B-cell lymphoma. The annual incidence rate is 0.3 per 100,000
population. We report a case of a 56-year-old male patient who presented with a
two-month history of nodules of varying sizes, some ulcerated, on the face,
abdomen, and upper limbs. Histopathological examination and immunohistochemical
study confirmed the diagnosis of primary cutaneous centrofollicular lymphoma.
Studies have shown an increased incidence of non-Hodgkin lymphomas in the last
decade. We report an infrequent case that should be kept as a differential
diagnosis of patients with nodules and cutaneous papules.