Linezolid Disposition during Peritonitis: A Case Report

Allcock, Nicole M; Krueger, Todd S; Manley, Harold J.; Kumar, Vinutha K.; Abdallah, Joseph F.

doi:10.1177/089686080402400108

Cited by 7 publications

(3 citation statements)

References 5 publications

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“…Vancomycin-resistant E. faecium has been reported but remains uncommon in PD patients. Limited data are available regarding the appropriate management of VRE peritonitis (145)(146)(147)(148). If VRE is ampicillin susceptible, ampicillin remains the drug of choice.…”

Section: Streptococcus and Enterococcusmentioning

confidence: 99%

Peritoneal Dialysis-Related Infections Recommendations: 2010 Update

et al. 2010

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Section: Streptococcus and Enterococcusmentioning

confidence: 99%

Peritoneal Dialysis-Related Infections Recommendations: 2010 Update

et al. 2010

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“…• Streptococcal and enterococcal peritonitis tend to be severe and are best treated with IP ampicillin (Opinion) (161). • Vancomycin-resistant Enterococcus faecium(VREF) has been reported but remains uncommon in PD patients; limited data are available on proper management (162)(163)(164)(165).…”

Section: Streptococcus and Enterococcusmentioning

confidence: 99%

Peritoneal Dialysis-Related Infections Recommendations: 2005 Update

et al. 2005

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“…Little information is available about the pharmacokinetics of antimicrobials in the peritoneal fluid after systemic administration, and much of it comes from case reports or short case series. Imipenem , meropenem , daptomycin , linezolid and colistin probably reach optimal concentrations in peritoneal fluid after systemic treatments and are good options for the treatment of peritonitis due to MDR bacteria. Other antimicrobials such as ertapenem and tigecycline reach inappropriate concentrations in peritoneal fluid, and so dose increases must be considered for the treatment of tertiary peritonitis.…”

Section: Common Difficult‐to‐treat Bacterial Infections Associated Wimentioning

confidence: 99%

Multidrug-resistant bacteria in solid organ transplant recipients

Cervera

Delden

Gavaldá

et al. 2014

Clinical Microbiology and Infection

146

115

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Bacteria are the leading cause of infections after solid organ transplantation. In recent years, a progressive growth in the incidence of multidrug-resistant (MDR) and extensively-drug-reistant (XDR) strains has been observed. While methicillin-resistant Staphylococcus aureus (MRSA) infection is declining in non-transplant and SOT patients worldwide, vancomycin-resistant enterococci, MDR/XDR Enterobacteriaceae and MDR/XDR non-fermenters are progressively growing as a cause of infection in solid organ transplant (SOT) patients and represent a global threat. Some SOT patients develop recurrent infections, related to anatomical defects in many cases, which are difficult to treat and predispose patients to the acquisition of MDR pathogens. As the antibiotics active against MDR bacteria have several limitations for their use, which include less clinical experience, higher incidence of adverse effects and less knowledge of the pharmacokinetics of the drug, and, in most cases, are only available for parenteral administration, it is mandatory to know the main characteristics of these drugs to safely treat SOT patients with MDR bacterial infections. Nonetheless, preventive measures are the cornerstone of controlling the spread of these pathogens. Thus, applying the Center for Disease Control and Prevention's and the European Society of Clinical Microbiology and Infectious Diseases's recommended antibiotic policies and strategies to control the transmission of MDR strains in the hospital setting is essential for the management of SOT patients.

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Linezolid Disposition during Peritonitis: A Case Report

Cited by 7 publications

References 5 publications

Peritoneal Dialysis-Related Infections Recommendations: 2010 Update

Peritoneal Dialysis-Related Infections Recommendations: 2010 Update

Peritoneal Dialysis-Related Infections Recommendations: 2005 Update

Multidrug-resistant bacteria in solid organ transplant recipients

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