Linear IgA bullous dermatosis

Egan, Conleth A.; Mb, .; Mrcpi, .; Zone, John J.

doi:10.1046/j.1365-4362.1999.00813.x

Cited by 104 publications

(104 citation statements)

References 111 publications

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“…3,5,6 However, mucosal lesions can be noted in up to 40% of drug-induced cases, which is still lower than the 80% involvement observed in the classical LABD. 7,11 Childhood LABD has been mostly associated with infections or drug ingestion and rarely with other conditions such as ulcerative colitis and autoimmune lymphoproliferative disease. 2,9 The most frequently reported drugs that can induce LABD in adults are antibiotics such as vancomycin, penicillin G, ampicillin, cefamandole, TMP-SMX, rifampin and sulfisoxazole, NSAID such as piroxicam, naproxen and diclofenac, interferon-gamma, interleukin-2, phenytoin, amiodarone, captopril, iodine contrast agent, somatostatin, lithium, furosemide and cyclosporine.…”

Section: Discussionmentioning

confidence: 99%

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Childhood linear IgA bullous disease induced by trimethoprim-sulfamethoxazole

Nantel-Battista¹,

Dhaybi²,

Hatami³

et al. 2010

J Dermatol Case Rep

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Background: Linear IgA bullous disease (LABD) is a rare mucocutaneous autoimmune subepidermal blistering disease that can affect children mostly of pre-school age. As many as two-thirds of LABD are related to drug ingestion, particularly certain antibiotics, non-steroidal anti-inflammatory drugs and diuretics.Main observation: We describe a 3-year-old boy who presented a CMV infection followed by LABD induced by trimtheporim-sulfametoxazole. To our knowledge, this is the first reported case of trimethoprim-sulfamethoxazole that was confirmed by a rechallenge.Conclusions: Most cases of drug-induced LABD are patients being treated with multiple systemic drugs that could induce the LABD. In the lack of suitable alternative treatment, the identification of the causative drug can be achieved by a rechallenge under close medical surveillance.

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Section: Discussionmentioning

confidence: 99%

“…4,7,8 However, the lesions may continue evolving for several weeks due to persistent autoimmunity that might take months to subside. 1,10 Our patient healed progressively within 2 weeks after stopping TMP-SMX.…”

Section: Figurementioning

confidence: 99%

Childhood linear IgA bullous disease induced by trimethoprim-sulfamethoxazole

Nantel-Battista¹,

Dhaybi²,

Hatami³

et al. 2010

J Dermatol Case Rep

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“…The prevalence of UC in LABD is three times more than in general population (7.1% compared to 0.05%) [11][12][13]. Whilst the risk of LABD in UC is currently unpredictable due to the lack of population studies.…”

Section: Discussionmentioning

confidence: 99%

Linear IgA Bullous Dermatosis Associated with Ulcerative Colitis in a 14-Year-Old Boy: A Case Report

Tozzo¹,

Negri²,

Salvatore³

2017

J Clin Case Rep

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“…Its pathogenesis is not exactly known but drugs and malignancies were found to be related with this disease (Egan and Zone, 1999). Dapsone and prednisolone are the options for the treatment (Sandoval et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of epidermoid lung carcinoma in a patient presenting with skin lesions

Yüksel¹,

Çelik²,

Şahin³

et al. 2013

jecm

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Article HistoryReceived 02 / 04 / 2013 Accepted 27 / 06 / 2013Skin lesions sometimes represent internal diseases or malignancies. Diagnosis of the associated disease could be important for the prognosis of the patient. Linear IgA bullous dermatosis (LABD) is a rare autoimmune subepidermal vesiculobullous disease. Tense vesicles and bullae, sometimes in an arcuate or linear pattern, are seen as the clinical feature. Although associations of various disorders such as gastrointestinal diseases, autoimmune diseases, malignancies with LABD have been reported, it is rare. We report a patient who was diagnosed epidermoid carcinoma of the lung after presentation with tense, annular bullous lesions and didn't respond to prednisolone and dapsone but was treated successfully by neoadjuvant chemotherapy and tumour reduction operation.

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Linear IgA bullous dermatosis

Cited by 104 publications

References 111 publications

Childhood linear IgA bullous disease induced by trimethoprim-sulfamethoxazole

Childhood linear IgA bullous disease induced by trimethoprim-sulfamethoxazole

Linear IgA Bullous Dermatosis Associated with Ulcerative Colitis in a 14-Year-Old Boy: A Case Report

Diagnosis of epidermoid lung carcinoma in a patient presenting with skin lesions

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