Linear atrophoderma of Moulin

Miteva, Ljubka; Nikolova, K.; Obreshkova, E.

doi:10.1111/j.1365-4632.2004.02221.x

Cited by 12 publications

(4 citation statements)

References 11 publications

(11 reference statements)

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“…Although all 28 clinical cases reviewed demonstrated atrophic‐appearing depressed plaques that followed the lines of Blaschko, telangiectasias were newly observed in several cases (4/28 cases) , and a bilateral presentation occurred rarely (2/28) . Of the 24 case reports that included histologic evaluation, new findings included perivascular lymphocytic infiltrates ( n = 15) , altered dermal collagen ( n = 8) , epidermal atrophy ( n = 3) , acanthosis ( n = 6) , decreased elastic tissue ( n = 2) , dilated dermal blood vessels ( n = 3) , dermal atrophy ( n = 1) , and plasma cell infiltrate ( n = 1) . Although these cases exhibited sufficient features to support a diagnosis of LAM, they suggested the possibility that LAM as originally described was limited in its scope and probably encompasses a broader set of features that fits within a spectrum of related disease.…”

Section: Discussionmentioning

confidence: 99%

Linear Atrophoderma of Moulin: A Distinct Entity?

Golian¹,

Echols²,

Pearl

et al. 2012

Pediatric Dermatology

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Linear atrophoderma of Moulin (LAM) is a rare dermatologic disorder characterized by a hyperpigmented atrophoderma that consistently follows the lines of Blaschko. There are many clinical and histologic similarities between LAM, atrophoderma of Pasini and Pierini (APP), and morphea, and whether LAM represents part of a disease spectrum or its own distinct entity is debated. This case of a 16-year-old boy with LAM supports the hypothesis that LAM, APP, and morphea are a spectrum of disorders rather than unique entities. Although the patient's overall clinical picture supports a diagnosis of LAM with hyperpigmented, depressed lesions following the lines of Blaschko and perivascular lymphocytic infiltrate on biopsy, the bilateral presentation typical of APP, collagen entrapment of eccrine ducts typical of morphea, and changes in dermal collagen illustrate features spanning all three disorders, suggesting a relationship between these conditions that represents a spectrum of disease. Furthermore, a review of all reported cases of LAM in the literature suggests an evolving definition beyond what Moulin and colleagues originally described, including features related to those of APP and morphea.

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Section: Discussionmentioning

confidence: 99%

Linear Atrophoderma of Moulin: A Distinct Entity?

Golian¹,

Echols²,

Pearl

et al. 2012

Pediatric Dermatology

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“…scribing epidermal nevi, linear inflamatory epidermal nevi, lichen striatus, or nevoid hypermelanosis. 6 The lesion of our case developed when she was 17 years old. She did not describe any prior inflammation.…”

Section: Introductionmentioning

confidence: 93%

Linear atrophoderma of Moulin on the neck

Demirci¹,

Altunay²,

Mertoğlu³

et al. 2011

J Dermatol Case Rep

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“…After the 5 first cases of linear atrophoderma reported by Moulin et al [1], 26 additional cases were described ([2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23], summarized in table 1). We include in our review of the literature a case of unilateral idiopathic atrophoderma described as a Pasini and Pierini entity but with lesions arranged along Blaschko's lines [24].…”

Section: Methodsmentioning

confidence: 99%

Linear Atrophoderma of Moulin: Report of 4 Cases and 20th Anniversary Case Review

Villani

Amini‐Adlé²,

Wagschal³

et al. 2013

Dermatology

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Background: Linear atrophoderma of Moulin (LAM) is a rare clinical entity which was first described by Moulin et al. in 1992. The diagnosis is clinical, characterized by acquired unilateral hyperpigmented, depressed band-like skin lesions following Blaschko's lines. The disease typically affects children or adolescents and has a good prognosis without evidence of long-term progression. To date, the pathophysiology is unclear. Different authors hypothesize that the disease is secondary to a mosaic manifestation as a result of a post-zygotic mutational event. Observations: Four patients (2 men, 2 women) had a history of unilateral band-like skin lesions located on the lower legs (50%) or the trunk (50%). Physical examination showed atrophic and hyperpigmented skin lesions along Blaschko's lines, which appeared during childhood in 3 cases and at the age of 20 in the last case. Lesions had progressed rapidly but seemed to have stabilized so far except for 1 case who presented spontaneous improvement. Histopathological examination revealed a normal epidermis with a hyperpigmented basal layer and a perivascular lymphocytic infiltrate in the dermis. Conclusion: LAM is a rare disease with 32 reported cases and remains an exclusion diagnosis. Since the problem is mainly esthetic, treatments should not be too aggressive.

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Linear atrophoderma of Moulin

Cited by 12 publications

References 11 publications

Linear Atrophoderma of Moulin: A Distinct Entity?

Linear Atrophoderma of Moulin: A Distinct Entity?

Linear atrophoderma of Moulin on the neck

Linear Atrophoderma of Moulin: Report of 4 Cases and 20th Anniversary Case Review

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