Linear arrangement of multiple congenital melanocytic nevi

Effendy, Isaak; Happle, Rudolf

doi:10.1016/0190-9622(92)70265-h

Cited by 23 publications

(26 citation statements)

References 9 publications

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“…The concept of mosaicism could give an attractive explanation of the linear distribution of the nevus as observed in our case and those of Happle and Effendy [6] . Indeed, a clonal outgrowth of cells, resulting from a mutation occurring at an early stage of embryogenesis, seems to be the support of the clinical features of these nevi following the lines of Blaschko.…”

Section: Introductionmentioning

confidence: 67%

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Blaschkolinear Congenital Melanocytic Nevus

Droitcourt¹,

Adenis-Lamarre²,

Ezzedine³

et al. 2009

Dermatology

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Section: Introductionmentioning

confidence: 67%

“…Focusing on large congenital melanocytic nevi, Effendy and Happle [6] reported in 1992 the first case of congenital melanocytic nevus, constituted of an association of multiple nevi with linear arrangement involving an arm, following the lines of Blaschko. This case and the present patient could be defined as having type II congenital melanocytic nevi [2] .…”

mentioning

confidence: 99%

Blaschkolinear Congenital Melanocytic Nevus

Droitcourt¹,

Adenis-Lamarre²,

Ezzedine³

et al. 2009

Dermatology

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“…The pigmented lesions were 0.6–2 cm in diameter. Other reported cases with congenital unilateral multiple melanocytic nevi had pigmented lesions that measured 0.1–3 cm in diameter [10, 11]. All these cases showed pigmented lesions at birth.…”

Section: Discussionmentioning

confidence: 99%

Acquired Unilateral Melanocytic Nevi in Otherwise Normal Skin

Nagai²,

Nishigori³

et al. 2008

Dermatology

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We describe a case with numerous melanocytic nevi in otherwise normal skin. A 5-year-old girl presented with more than 100 small pigment lesions on her left arm, shoulder and upper back without underlying light brown macule. The pigment lesions were first found on her left forearm at 3 months old and gradually increased along with her growth. Skin biopsy from a pigmented lesion shows a pathological change in compound-type melanocytic nevus without any atypical changes. Speckled lentiginous nevus is known to have multiple melanocytic lesions on the underlying brown macule from birth. Partial unilateral lentiginosis is characterized by unilateral lentigines with histopathological changes in lentigo but not melanocytic proliferation in the dermis. Agminated melanocytic nevi tend to be clustered together in a circumscribed area, whereas in the present case melanocytic nevi were segmentally arranged but not agminated. We consider that this is an unusual type of mosaicism of melanocytic disorders.

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“…Agminated melanocytic naevus differs from naevus spilus by the lack of clinically visible background pigmentation and the histology of a junctional or compound melanocytic naevus (3). Agminated naevi are rarely observed (3)(4)(5)(6)(7)(8)(9)(10)(11), compared with agminated blue naevi and agminated Spitz naevi. ln this article we describe a case of malignant melanoma arising from an acquired agminated melanocytic naevus.…”

mentioning

confidence: 90%