Linear and Annular Lupus Panniculitis of the Scalp

Mitxelena, J.; Martínez-Peñuela, Ana; Córdoba, Alicia; Yanguas, I.

doi:10.1016/j.adengl.2012.12.012

Cited by 10 publications

(15 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite the appearance of LEP surface with DLE features, other scalp abnormalities could possibly be presented, including scarring alopecia (five cases, 25%), erythema (14 cases, 70%), induration (five cases, 25%), tenderness (six cases, 30%), mass (two cases, 10%), skin atrophy (two cases, 10%), and follicular papule (5%) . Although, there were 20% of the alopecia cases without other abnormal physical findings on the scalp.…”

Section: Discussionmentioning

confidence: 96%

“…The histopathologic examination revealed a lobular lymphocytic panniculitis (100%) with mucin deposition (65%), hyaline fat degeneration (60%), basal vacuolization or thickening of basement membrane (20%), and epidermal changes of DLE (30%) . The infiltration by plasma cell (15%) and nodular lymphoid aggregation (15%) was also illustrated in Figure , while direct immunofluorescences (DIF) was positive in 20%, comprising of IgM, IgG, and C3 at basement membrane, and follicular epithelium as typical LEP . Besides, the immunohistochemical studies of LPS revealed the presence of CD3 + , CD4 + , CD8 + , CD56‐T cell with normal CD4: CD8 ratio and no abnormal polyclonality on T‐cell receptor gene rearrangement similar to the typical LEP …”

Section: Discussionmentioning

confidence: 99%

“…The scalp lupus panniculitis could be a solitary presentation, while multiple sites were also involved with other associated clinical presentations, including LEP of parotid gland and eyelid, axilla, bilateral cheeks and upper arms, subcutaneous nodule on the elbow, left periorbital erythema, and swelling of the face with progression to facial hemiatrophy, facial nerve paralysis, and enophthalmos …”

Section: Discussionmentioning

confidence: 99%

“…However, the recurrence rate was high in 35%. Considerably, four cases (20%) developed SLE (two cases with lupus nephritis) during the median duration of 9 (2–15) years of follow‐up, and one case had Parry‐Romberg syndrome, although three cases with SLE development during follow‐up were noted with positive ANA and two cases had previous DLE …”

Section: Discussionmentioning

confidence: 99%

“…Once the dermis is also involved, the follicles are often consequently destroyed with a scarring alopecia. 8,11,14,15 erythema (14 cases, 70%), 3,7-10,14-20 induration (five cases, 25%), 8,14,16,17,18 tenderness (six cases, 30%), [7][8][9]16,18,19 mass (two cases, 10%), 19,21 skin atrophy (two cases, 10%), 7,20 and follicular papule (5%). 15 Although, there were 20% of the alopecia cases without other abnormal physical findings on the scalp.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Distinctive lupus panniculitis of scalp with linear alopecia along Blaschko's lines: a review of the literature

2018

View full text Add to dashboard Cite

Lupus panniculitis of the scalp (LPS) is a rare and distinctive clinical feature of lupus erythematosus panniculitis (LEP) with linear alopecia along Blaschko's lines. In this study, we investigated clinical features and treatments of LPS by literature review of articles in the English language from PubMed and SCOPUS databases up to April 2018. The following key words, "lupus panniculitis, "lupus erythematosus panniculitis", "lupus profundus", "head", and "scalp", were used. Twenty cases of LPS were identified (mean age = 26.4 [10-53] years, female: male ratio = 1:1, mean disease duration = 86.89 [8-336] weeks). The most commonly affected areas of scalp included parietal (70%), frontal (45%), temporal (40%), occipital (30%), and vertex (10%), along 70% of Blaschko's lines with morphologic lesions linear, annular, arch-shaped, and ulcer. Besides, ANA (60%) was in particular noted. Hydroxychloroquine, oral prednisolone, intralesional corticosteroid, and methotrexate were the most common treatments, with complete response after an average period of 8.08 (2-12) weeks. Systemic lupus erythematosus (SLE) was developed in four cases (20%) during follow-up, with high recurrence of 35%. We reported distinctive and rare cases of LPS.The continuing follow-up was highly recommended to avoid probable recurrence and SLE development.

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Distinctive lupus panniculitis of scalp with linear alopecia along Blaschko's lines: a review of the literature

2018

View full text Add to dashboard Cite

show abstract

Arc-Shaped Furrow on the Forehead Extending From Linear Alopecia on the Vertex

2022

View full text Add to dashboard Cite

A man in his 50s presented to our dermatology department with an asymptomatic, arcshaped, depressed skin groove on the left side of his forehead, frontal scalp, and vertex area. Localized linear hair loss and hair thinning on the left scalp area were observed. The patient reported that when the lesion had begun to appear, approximately 10 years earlier, he had received 2 doses of intralesional steroid via injection on a small bald patch on the vertex. Thereafter, the lesion gradually progressed to the frontal scalp and eventually made a linear furrow on the left side of his forehead.Physical examination revealed 2 long, curved-line, depressed, alopecic patches on the left side of the vertex and frontal scalp area extending to the left eyebrow (Figure , A and B). The lesions measured (length × width) 7 × 2 cm and 6 × 1 cm, respectively. Dermoscopic examination of the alopecic area revealed several short vellus hairs, yellow dots, and honeycomb hyperpigmentation; however, broken hairs were not seen. The result of a hair pull test was negative. The patient denied any trauma history and had no history of connective tissue disease nor any evidence of systemic involvement, such as arthralgia, photosensitivity, or skin rashes. Skin biopsies were performed on the left side of the vertex and the forehead. Histopathologic findings of the 2 biopsy specimens were identical (Figure, C and D).

show abstract

Lupus profundus limited to a site of trauma: Case report and review of the literature

Castrillón

Murrell

2017

International Journal of Women's Dermatology

View full text Add to dashboard Cite

Lupus erythematosus profundus (LEP) is a rare form of chronic cutaneous lupus erythematosus. We report on a case of a 56-year-old Caucasian woman who presented with a single, persistent, painful rash on the left hip and lateral aspect of the left upper thigh, which had been present for 2.5 years. The patient had a history of previous injury to this area before the rash started. Clinical findings showed an inflamed, hyperpigmented, and indurated plaque with a linear skin invagination and no associated systemic symptoms. A skin biopsy test result confirmed the diagnosis of LEP and the clinical and laboratory examinations ruled out systemic lupus erythematosus. After 2 months of treatment with methotrexate 20 mg weekly and 1 month of prednisolone 7.5 mg daily, the skin rash improved considerably. We also present a brief review of the epidemiology, etiology, clinical features, histopathology, laboratory findings, differential diagnosis, and treatment of LEP.

show abstract

Linear and Annular Lupus Panniculitis of the Scalp

Cited by 10 publications

References 8 publications

Distinctive lupus panniculitis of scalp with linear alopecia along Blaschko's lines: a review of the literature

Distinctive lupus panniculitis of scalp with linear alopecia along Blaschko's lines: a review of the literature

Arc-Shaped Furrow on the Forehead Extending From Linear Alopecia on the Vertex

Lupus profundus limited to a site of trauma: Case report and review of the literature

Contact Info

Product

Resources

About