Linear Accelerator Radiosurgery for Meningiomas in and around the Cavernous Sinus

Abstract

This study indicates that linear accelerator radiosurgery can achieve a high control rate of meningiomas involving the cavernous sinus with no mortality and a low incidence of morbidity.

Fractionated Stereotactic Radiation Therapy in the Management of Benign Cavernous Sinus Meningiomas

“…No predictors of clinical response could be identified [33]. In radiosurgery experience, improved cranial nerve function was more likely after treatment of patients with deficits present for > 1 year and those treated for primary meningiomas [30,40]. In our analysis, 19.3% of the patients showed improvement in preexisting neurologic deficits, like reduction of diplopia, exophthalmos, trigeminal dysesthesia, and headache symptoms after a median follow-up of 6.5 years.…”

“…However, in none of these reports the imaging criteria for response after radiosurgery were enumerated. Only in one analysis, a quantitative measurement of tumor response after linac-based radiosurgery was provided [40]. These authors reported a tumor reduction of at least 20% in 60% of patients.…”

Fractionated Conformal Radiotherapy in the Management of Cavernous Sinus Meningiomas: Long-Term Functional Outcome and Tumor Control at a Single Institution

“…In recent series of SRS for CSM, mean tumor volume ranged from 4.3 to 14.7 cm 3 (11,(18)(19)(20)(21)(22)(23)(24)(25)(26). Conversely, in recent FCR series, tumor volumes ranged from 11.31 to 35.2 cm 3 (11,(13)(14)(15).…”

Central and Paracentral Visual Field Defects and Driving Abilities

“…Other procedures associated with iatrogenic VF loss include radiation and ENT surgery of the sinuses, neuro- and cardiovascular surgery [42, 87, 103, 108, 123, 137, 153, 162, 183, 188, 200]. …”