LINE-1 and SINE-B1 mapping and genome diversification in Proechimys species (Rodentia: Echimyidae)

Abstract

This study aimed to understand the impact of LINE-1 and SINE-B1 retroelements on the architecture and karyotypic diversification of five rodent species of the genus Proechimys from different regions of the Amazon. Karyotype comparisons were performed using fluorescent interspecific in situ hybridization. The L1 and B1 retroelements showed a non-random arrangement and a conserved pattern when the genomes of the five species of Proechimys were compared, including the two cytotypes of Proechimys guyannensis. The signal homeology among the chromosomes and the degree of similarity among the formed clusters indicate rearrangements such as fusion/fission, and demonstrates that these retroelements can behave as derived characters shared in Proechimys. The differentiated distribution and organization of these retroelements in the karyotypes and in the chromosomal fiber, respectively, may represent a strong indication of their role as generating sources of karyotypic diversity in the genus Proechimys and provide insights into the evolutionary relationships between taxa.

Karyotypes of Manatees: New Insights into Hybrid Formation (Trichechus inunguis × Trichechus m. manatus) in the Amazon Estuary

“…The genomic instability caused by the activation and mobilization of TEs in hybrids can promote the emergence of new chromosomal rearrangements, as observed in marsupials [ 44 ]. In bats and rodents, LINE-1 is proposed to be involved in the genomic reorganization of these groups [ 45 , 46 ]. Considering this information, it is plausible to propose that the heteromorphism of pair 3 and the six chromosomes with unique banding patterns in the “Vitor’s” karyotype (which pairs could not be identified) may have their origin linked to new chromosomal rearrangements produced from of the activity of TEs during the hybridization process.…”

THE SOURCES OF GENOME VARIABILITY AS DOMESTICATION DRIVERS (review)

“…У группы близкородственных видов щетинистой крысы обнаружены выраженные межвидовые различия по хромосомному позиционированию ретротанспозонов LINE и SINE, что позволило высказать предположение об их вовлеченности в видообразование (36).…”