LINC00963 Promotes Cisplatin Resistance in Esophageal Squamous Cell Carcinoma by Interacting with miR-10a to Upregulate SKA1 Expression

Hu, Dongxin; Ma, Anqun; Lu, Hongda; Gao, Zhen; Yu, Yue; Fan, Jiaming; Liu, Shang; Wang, Yancheng; Zhang, Mingyan

doi:10.1007/s12010-024-04897-4

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Lncrnas Upregulated In Escc1

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2024

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“…A study revealed that lncRNA HCP5/miR-216a-3p/PDK1 enhanced radiotherapy resistance in KYSE30 and TE-1 cells by activating the AKT signaling pathway ( 114 ). Similarly, LINC00963/miR-10a/spindle and kinetochore associated complex subunit 1 was found to increase cisplatin resistance in TE-1 and TE-1/DDP cells, thereby promoting CDX growth ( 115 ). Furthermore, after cisplatin treatment, lncRNA non-coding repressor of NFAT was upregulated, contributing to cisplatin resistance by downregulating miR-31 in KYSE510 ( 116 ).…”

Section: Lncrnas Upregulated In Esccmentioning

confidence: 99%