volume 10, issue 6, P1523-1533 2018
DOI: 10.18632/aging.101488
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Yafei Ye, Shengnan Yang, Yanping Han, Jingjing Sun, Lijuan Xv, Lina Wu, Yongfeng Wang, Liang Ming

Abstract: Long intergenic non-coding RNA Linc00472 has been considered as a tumor suppressor in some cancers. However, the function and mechanism of Linc00472 in colorectal cancer has not been well elucidated. In this study, we found that Linc00472 was down-regulated in colorectal cancer tissues and cells. Elevated Linc00472 expression suppressed proliferation and induced apoptosis in colorectal cancer cells. Moreover, Linc00472 acted as a competing endogenous RNA (ceRNA) of miR-196a to release programmed cell death 4 (…

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