Linagliptin electrochemical sensor based on carbon nitride-β-cyclodextrin nanocomposite as a modifier

Gandomi, Faezeh; Khosrowshahi, Elnaz Marzi; Sohouli, Esmail; Aghaei, Mohammad; Mohammadnia, Maryam Saleh; Naghian, Ebrahim; Rahimi‐Nasrabadi, Mehdi

doi:10.1016/j.jelechem.2020.114697

Cited by 30 publications

(7 citation statements)

References 45 publications

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“…Graphitic carbon nitride has a layered 2D structure, with the graphitic planes connected by amino groups, with good conductivity and is normally formed through the pyrolysis of melamine. This layered material has been combined with graphite, mineral oil, and β-CD to form a carbon paste electrode and employed in the electrochemical detection of linagliptin, a hypoglycemic drug molecule [149]. A carboxymethyl-β-cyclodextrin, serving as the polyanion, was layered with Mg-Al LDH and deposited onto a glassy carbon electrode to give the capacitive detection of acetaminophen.…”

Section: Other Conducting Materials Combined With Cyclodextrinsmentioning

confidence: 99%

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

et al. 2021

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Supramolecular chemistry, although focused mainly on noncovalent intermolecular and intramolecular interactions, which are considerably weaker than covalent interactions, can be employed to fabricate sensors with a remarkable affinity for a target analyte. In this review the development of cyclodextrin-based electrochemical sensors is described and discussed. Following a short introduction to the general properties of cyclodextrins and their ability to form inclusion complexes, the cyclodextrin-based sensors are introduced. This includes the combination of cyclodextrins with reduced graphene oxide, carbon nanotubes, conducting polymers, enzymes and aptamers, and electropolymerized cyclodextrin films. The applications of these materials as chiral recognition agents and biosensors and in the electrochemical detection of environmental contaminants, biomolecules and amino acids, drugs and flavonoids are reviewed and compared. Based on the papers reviewed, it is clear that cyclodextrins are promising molecular recognition agents in the creation of electrochemical sensors, chiral sensors, and biosensors. Moreover, they have been combined with a host of materials to enhance the detection of the target analytes. Nevertheless, challenges remain, including the development of more robust methods for the integration of cyclodextrins into the sensing unit.

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Section: Other Conducting Materials Combined With Cyclodextrinsmentioning

confidence: 99%

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

et al. 2021

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“…In addition to the above compounds, ordered mesoporous silicas and mesoporous carbon, and 2D layered materials with good conducting properties and high surface areas have been discovered in the development of sensors, including CDs as the molecular recognition agent [255][256][257]. For a parallel connected supercapacitor and dye-sensitized solar cell, β-CD is sulfonated, thermally crosslinked with PVP, and incorporated with MnCO 3 nanoparticles.…”

Section: Cds In Solar Energymentioning

confidence: 99%

Cyclodextrins: Structural, Chemical, and Physical Properties, and Applications

et al. 2021

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Due to their unique structural, physical and chemical properties, cyclodextrins and their derivatives have been of great interest to scientists and researchers in both academia and industry for over a century. Many of the industrial applications of cyclodextrins have arisen from their ability to encapsulate, either partially or fully, other molecules, especially organic compounds. Cyclodextrins are non-toxic oligopolymers of glucose that help to increase the solubility of organic compounds with poor aqueous solubility, can mask odors from foul-smelling compounds, and have been widely studied in the area of drug delivery. In this review, we explore the structural and chemical properties of cyclodextrins that give rise to this encapsulation (i.e., the formation of inclusion complexes) ability. This review is unique from others written on this subject because it provides powerful insights into factors that affect cyclodextrin encapsulation. It also examines these insights in great detail. Later, we provide an overview of some industrial applications of cyclodextrins, while emphasizing the role of encapsulation in these applications. We strongly believe that cyclodextrins will continue to garner interest from scientists for many years to come, and that novel applications of cyclodextrins have yet to be discovered.

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“…Many electrochemical reactions are facilitated by reducing the overvoltage in the presence of catalytic nanoparticles. This property of nanoparticles can also affect the reversibility of some oxidation-reduction reactions, which are typically irreversible on the unmodified electrode [4,5].…”

Section: Introductionmentioning

confidence: 99%

Highly sensitive electrochemical azaperone sensor based on magnetic silica –NH2-CS2 in the ostrich meat and rat plasma and its comparison with HPLC–MS/MS

et al. 2022

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Azaperone is a very important phenylbutanone-based neurotransmitter used in the treatment of some animal (veterinary) clinics. This compound has various nerve and tendon stabilizing agents on livestock and animals. Muscular injection of azaperone is used to reduce stress in livestock and reduce their acting. In the present work, Fe3O4@SiO2-NH2/CS2 nanocomposite was synthesized and thoroughly characterized using FE-SEM, FT-IR, and XRD technique. The glassy carbon electrode was then modified with nanocomposite to fabricate a sensor named GCE/Fe3O4@SiO2-NH2/CS2. The application of modified electrode was tested for analysis of azaperone in ostrich meat and rat plasma. The electrochemical behavior of azaperone was tested using differential pulse and cyclic voltammetry. In Briton–Robinson buffer solution (pH = 6), azaperone had an oxidation peak at 0.82 V. Cyclic voltammetry studies indicated that the azaprone oxidation process on the modified electrode is irreversible. Experimental variables, including pH and accumulation time were optimized by monitoring the cyclic voltammetry responses toward azaperone peak current. Measurement of azaperone by differential pulse voltammetry technique showed linearity of anodic peak current vs. azaperone concentration in a range of 0.01–100.0 μM with detection and quantification limits of 3 nM and 10 nM, respectively. Also, the effect of disturbance of some species as possible interferers on the electrochemical response of azaperone was checked out. Finally, the capability of the fabricated sensor for azaperone measurement was successfully tested in ostrich meat and rat plasma as real samples. Graphical abstract

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Linagliptin electrochemical sensor based on carbon nitride-β-cyclodextrin nanocomposite as a modifier

Cited by 30 publications

References 45 publications

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

Cyclodextrins as Supramolecular Recognition Systems: Applications in the Fabrication of Electrochemical Sensors

Cyclodextrins: Structural, Chemical, and Physical Properties, and Applications

Highly sensitive electrochemical azaperone sensor based on magnetic silica –NH2-CS2 in the ostrich meat and rat plasma and its comparison with HPLC–MS/MS

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