Limited joint mobility (LJM) in elderly subjects with type II diabetes mellitus

Abate, Michele; Schiavone, Cosima; Pelotti, Patrizia; Salini, Vincenzo

doi:10.1016/j.archger.2010.09.011

Cited by 72 publications

(82 citation statements)

References 77 publications

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“…[4][5][6][7][8][9] Diabetics are four times more likely to have musculoskeletal disorders compared to non-diabetics 6 with the shoulder being one of the joints most affected by the disease. 10 Previous studies show that diabetics have higher prevalence of shoulder pain and injuries compared to non-diabetics.…”

Section: Introductionmentioning

confidence: 99%

“…6,7,[10][11][12][13][14] Specifically, diabetics are 3-9 times more likely to have frozen capsulitis and 5 times more likely to have rotator cuff tears compared to non-diabetics. 4,12,15 Additionally, diabetics are reported to have thickened supraspinatus and biceps tendons 16 along with decreased ROM in shoulder abduction and flexion 4,5 an impaired tendon-bone healing capacity 17 and difficulty regaining range of motion (ROM) after a surgery. 18,19 The musculoskeletal symptoms described above are attributed to mechanical changes in connective tissue due to formation of advanced glycation end products (AGEs).…”

Section: Introductionmentioning

confidence: 99%

“…18,19 The musculoskeletal symptoms described above are attributed to mechanical changes in connective tissue due to formation of advanced glycation end products (AGEs). 4 The AGEs are formed from a reaction that occurs from bonding of sugar and amino acid. 4 The AGEs cause increased crosslinking between collagen fibers and increase stiffness and brittleness of the connective tissue.…”

Section: Introductionmentioning

confidence: 99%

“…4 The insertion of the rotator cuff on the greater tubercle corresponds to an area of poor blood supply [21][22][23] which may further contribute to accumulation of AGEs.…”

mentioning

confidence: 99%

“…4 The AGEs are formed from a reaction that occurs from bonding of sugar and amino acid. 4 The AGEs cause increased crosslinking between collagen fibers and increase stiffness and brittleness of the connective tissue. This change in mechanical property makes the tissue more susceptible to failure under stress.…”

mentioning

confidence: 99%

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Effects Of 7-week Shoulder Exercise Intervention On Joint Mobility, Strength, And Function In Diabetics And Non-diabetics

Oyama

Sosa

Romero

2015

Medicine &Amp; Science in Sports &Amp; Exercise

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Abbreviations: ROM, range of motion; IR, internal rotation; ER, external rotation; DASH, disabilities of the arm, shoulder and hand; SPADI, shoulder pain and disability index IntroductionIn the United States, the prevalence of diabetes has increased from 5.5% to 9.3% within past decades 1 with the disease currently affecting 29.1 million people.2 Diabetes is commonly associated with conditions such as cardiovascular disease and long-term negative effects on various organs in the body such as kidneys and eyes.3 However, diabetes has also been shown to affect the musculoskeletal system. [4][5][6][7][8][9] Diabetics are four times more likely to have musculoskeletal disorders compared to non-diabetics 6 with the shoulder being one of the joints most affected by the disease. 10 Previous studies show that diabetics have higher prevalence of shoulder pain and injuries compared to non-diabetics. 6,7,[10][11][12][13][14] Specifically, diabetics are 3-9 times more likely to have frozen capsulitis and 5 times more likely to have rotator cuff tears compared to non-diabetics. 4,12,15 Additionally, diabetics are reported to have thickened supraspinatus and biceps tendons 16 along with decreased ROM in shoulder abduction and flexion 4,5 an impaired tendon-bone healing capacity 17 and difficulty regaining range of motion (ROM) after a surgery. 18,19 The musculoskeletal symptoms described above are attributed to mechanical changes in connective tissue due to formation of advanced glycation end products (AGEs). 4 The AGEs are formed from a reaction that occurs from bonding of sugar and amino acid. 4 The AGEs cause increased crosslinking between collagen fibers and increase stiffness and brittleness of the connective tissue. This change in mechanical property makes the tissue more susceptible to failure under stress. 20While accumulation of AGEs naturally occurs with aging, the process is accelerated in diabetics due to high blood glucose concentration and decreased peripheral blood flow. 4 The insertion of the rotator cuff on the greater tubercle corresponds to an area of poor blood supply [21][22][23] which may further contribute to accumulation of AGEs.Stretching and strengthening exercises focused on improving rotator cuff strength and restoring balance between the muscles that stabilize and rotate scapula are used in prevention and treatment of shoulder pain. [21][22][23][24][25][26][27][28] Effectiveness of this approach has been demonstrated in both healthy individuals and patients with various shoulder injuries. Despite the increased prevalence of shoulder pain among diabetics, there has only been one study that examined the effect of a physiotherapy program specifically in this population. 29 The study demonstrated that implementation of a physiotherapy program resulted in decreased pain level and improved shoulder function in diabetic patients who had shoulder pain. 29 However, this study did not have a comparison group without diabetes; therefore it is unknown how changes in tissue property caused by diabetes moderates...

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…4 The insertion of the rotator cuff on the greater tubercle corresponds to an area of poor blood supply [21][22][23] which may further contribute to accumulation of AGEs.…”

mentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Effects Of 7-week Shoulder Exercise Intervention On Joint Mobility, Strength, And Function In Diabetics And Non-diabetics

Oyama

Sosa

Romero

2015

Medicine &Amp; Science in Sports &Amp; Exercise

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Fibular motor nerve conduction studies and ankle sensorimotor capacities

et al. 2012

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Introduction Nerve conduction studies provide information regarding the status of the peripheral nerve, but relationships with sensorimotor capacities that influence mobility have not been defined. Methods A secondary analysis was conducted of data from 41 older subjects (20 women, age 69.1 ± 8.3 years), 25 with diabetic neuropathy of varying severity, and 16 without diabetes or neuropathy. Measurements included routine fibular motor nerve conduction studies and laboratory-based determination of ankle inversion/eversion proprioceptive thresholds and ankle inversion/eversion motor function. Results Independent of age, fibular amplitude correlated robustly with ankle inversion/eversion proprioceptive thresholds (R2 = .591, p < .001), moderately with ankle inversion and eversion rates of torque generation (R2 = .216; p = .004 and R2 = .200; p = .006, respectively), and more strongly when fibular motor amplitude was normalized for body mass index (R2 = .350; p < .001 and R2 = .275; p = .001). Discussion Fibular motor amplitude was strongly associated with ankle sensorimotor capacities that influence lateral balance and recovery from perturbations during gait. The results suggest that nerve conduction study measures have potential for an expanded clinical role in evaluating mobility function in the population studied.

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