Limited duration of hypersensitivity reactions to contrast and exact documentation of such adverse events

Boehm, Ingrid

doi:10.1136/rapm-2019-100792

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…If this time is within 2‐6 months, 50% of patients tested show positive results, decreasing to up 18% for patients tested at other time points (earlier than 2 months or later than 6 months) 6 . The reason for this fact may be the limited duration of skin reactivity due to IgE clearance 35 …”

Section: Immediate Hypersensitivity Reactionsmentioning

confidence: 99%

Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity

Torres

Trautmann

Böhm

et al. 2021

Allergy

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Immediate and nonimmediate hypersensitivity reactions to iodinated contrast media (ICM) have been reported to occur in a frequency of about 0.5%‐3% of patients receiving nonionic ICM. The diagnosis and management of these patients vary among guidelines published by various national and international scientific societies, with recommendations ranging from avoidance or premedication to drug provocation test. This position paper aims to give recommendations for the management of patients with ICM hypersensitivity reactions and analyze controversies in this area. Skin tests are recommended as the initial step for diagnosing patients with immediate and nonimmediate hypersensitivity reactions; besides, they may also help guide on tolerability of alternatives. Re‐exposition or drug provocation test should only be done with skin test‐negative ICMs. The decision for performing either re‐exposition or drug provocation test needs to be taken based on a risk‐benefit analysis. The role of in vitro tests for diagnosis and pretreatment for preventing reactions remains controversial.

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Section: Immediate Hypersensitivity Reactionsmentioning

confidence: 99%

Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity

Torres

Trautmann

Böhm

et al. 2021

Allergy

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show abstract

“…If this time is within 2-6 months, 50% of patients tested show positive results, decreasing to up 18% for patients tested at other time points (earlier than 2 months or later than 6 months) [6]. The reason for this fact is the limited duration of skin reactivity due to IgE clearance [37]. b) Practical Statement: SPT and IDT should be performed according to EAACI Guidelines [38].…”

Section: -How To Perform Skin Testing?mentioning

confidence: 99%

Practice Parameters for Diagnosing and Managing Iodinated Contrast Media Hypersensitivity

Torres¹,

Trautmann²,

Böhm³

et al. 2020

Preprint

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Immediate and non-immediate hypersensitivity reactions to iodinated contrast media (ICM) have been reported to occur in a frequency of about 0.5-3% of patients receiving non-ionic ICM. The diagnosis and management of these patients is controversial among guidelines published by various national and international scientific societies, with recommendations ranging from avoidance or premedication to drug provocation test. This position paper aims to give recommendations for the management of patients with ICM hypersensitivity reactions and analyze controversies in this area. Skin tests are recommended as the initial step for diagnosing patients with immediate and non-immediate hypersensitivity reactions; besides, they may also help guide on tolerability of alternatives. Drug provocation test is the gold-standard; although, as it is a risky procedure, the decision for performing it needs to be taken based on a risk-benefit analysis. Another source of controversy is the role of in vitro tests for diagnosis and pretreatment for preventing reactions.

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“…We appreciate the comments of Kalangara and Kuruvilla and Boehm 1 2. In our paper, we discussed the topics that Kalangara and Kuruvilla elucidated on.…”

mentioning

confidence: 96%

Reply to Kalangara and Kuruvilla and Boehm

Benzon¹,

Katz

Nagpal

et al. 2019

Reg Anesth Pain Med

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Limited duration of hypersensitivity reactions to contrast and exact documentation of such adverse events

Cited by 4 publications

References 5 publications

Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity

Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity

Practice Parameters for Diagnosing and Managing Iodinated Contrast Media Hypersensitivity

Reply to Kalangara and Kuruvilla and Boehm

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