Acquisition and interocular transfer of adaptation to optical transformations of input were examined in strabismic and orthotropic subjects. Distinct patterns of behavior were displayed by three groups: strabismic alternating suppressors, strabismic and orthotropic constant suppressors, and orthotropes with normal binocularity of vision. It is suggested that these behaviors result from the way in which visual space is represented in each group, an outcome of the pattern of use of the eyes during early development. The conditions for modification of the representation of visual space appear to parallel those for initial acquisition.Two principal types of monocular suppression are found among strabismic individuals: an alternating form, in which vision in each eye is suppressed part of the time, and a constant form, in which vision in one eye is consistently suppressed. We recently examined visually guided reaching in strabismic individuals and in persons with normal binocularity of vision (Mann, Hein, & Diamond, 1979). Like persons in whom the two eyes converge at the same point in visual space, alternating suppressors localized targets equivalently when using either eye, while constant suppressors did not. The discrepancies in target localization displayed by constant suppressors were attributed to their utilization of information about the posture of the dominant eye in localizing targets viewed monocularly by either eye. This implies that when targets are viewed by the normally suppressed eye, retinal locus information from that eye is combined with postural information from the dominant eye. The necessity for constant suppressors to rely upon information about the posture of the occluded eye was viewed as a result of the way in which a representation of visual space had been acquired during early development. This representation is assumed to incorporate the correspondence between direction of objects in space, retinal loci of images, and the set of postures that the eye can assume. Constant suppression of vision in one eye