Limb trauma: the use of an advanced wound care device in the treatment of full-thickness wounds

Abstract

This is an observational case series of 15 patients with full-thickness traumatic wound defects treated with a dermal substitute. There were 8 male and 7 female patients with a mean age of 36.6 years. Eight patients had trauma to the lower limbs and 7 were of the upper limbs, with the average lesion size 104.4 cm2 (range 6–490 cm2). The time to complete healing had a mean average time of 26.8 days (range 16–60 days). All patients went on to successful repair with 6 patients requiring a second application of the substitute and 5 patients needing split thickness skin grafts. Infection was recorded in one patient.

Proximally Based Anterolateral-Thigh (ALT) Flap for Knee Reconstruction: An Advancement Propeller Perforator Flap

“…Adequate coverage of this region is often challenging for plastic and orthopedic surgeons. The complexity of the problem can also be compounded by the presence of exposed bone or tendon, an open joint or the presence of a synthetic device or prosthesis [2,3].…”

Use of a Bioartificial Dermal Regeneration Template for Skin Restoration in Combat Casualty Injuries

“…In a series of 15 patients with traumatic mixed upper and lower extremity full-thickness injuries, use of a dermal substitute enabled healing in all cases: six of 15 required a second application of the dermal substitute, and five patients required skin grafting to complete healing. Infection was reported in one case [17].…”

Allogeneic epidermal substitutes in the treatment of chronic diabetic leg and foot ulcers

“…Micropores (diameter of 40 µm, 6250 poers/cm 2 ) allow neovascularization of the construct after the application, and cellular migration from the superior to the inferior face of the sheet, that is, the face in contact with a wound bed. [7] HYAFF11 forms a two-dimensional matrix, 20-mm thick, for epidermal substitutes, and a three-dimensional scaffold for dermal constructs.…”