Limb Salvage in Bone Sarcomas in Patients Younger Than Age 10

Allograft Reconstruction After Sarcoma Resection in Children Younger Than 10 Years Old

“…However, there are very few references in the literature [25] considering exclusively patients younger than 10 years old, a population that for reasons previously addressed is a particular difficulty for reconstructive surgeons. At last followup, 18 of our 22 patients had an average functional score of 27 points (range, 20-30 points).…”

“…Surgical options for patients at this very early age include amputation, rotationplasty [6,13,26], or tumor resection followed by some type of reconstruction: expandable prosthesis [1,3,8,14,22,23,27], distraction osteogenesis [11], autologous grafts [11], or allografts [2,5,7,15,16,19,24,25]. Although amputation is still an option in those patients with extensive sarcoma and who are nonresponsive to chemotherapy, cosmetic, emotional, and functional limitations are obvious [28].…”

Failure rates and functional results for intercalary femur reconstructions after tumour resection

“…In contrast, biological reconstruction requires a lengthy period of non-weight bearing to allow for union and graft hypertrophy [5,6,15]. However, biological reconstructions allow the opportunity to restore bone stock after massive resection, which is a significant advantage, particularly in the paediatric and young patients population [23,24,35].…”

Current Role for Resection of Thoracic Metastases in Children and Young Adults - Do we Need Different Strategies for this Population?

“…Good medium and long-term results have been published after this careful selection firstly for sarcoma tumors [4] and for other histological types such as renal tumors, testicular tumors, and others [5,6]. There is a specific population which is increasing consisting of young patients treated for mesenchymal tumors that respond to treatment [7]. This is a consequence of the efficacy of new chemotherapy drugs.…”