Limb fat-free mass and fat mass reference values by dual-energy X-ray absorptiometry (DEXA) in a 20–80 year-old italian population

Coin, Alessandra; Giannini, Sandro; Minicuci, Nadia; Rinaldi, Giulia; Pedrazzoni, M.; Minisola, Salvatore; Rossini, Maurizio; Puente, Antonio Del; Inelmen, Eminè Meral; Manzato, Enzo; Sergi, Giuseppe

doi:10.1016/j.clnu.2012.01.012

Cited by 71 publications

(30 citation statements)

References 29 publications

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“…To date, research has found that in healthy populations, the right arm has slightly less fat and slightly more lean tissue than the left arm 17 and that for those with severe lymphedema, large increases in the volumes of fat and lean tissue were found in the affected side. 7 Both of these studies failed to take dominance into consideration, which may have impacted the findings.…”

Section: Discussionmentioning

confidence: 98%

Tissue Composition Changes and Secondary Lymphedema

Dylke

Ward

Meerkin³

et al. 2013

Lymphatic Research and Biology

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Section: Discussionmentioning

confidence: 98%

Tissue Composition Changes and Secondary Lymphedema

Dylke

Ward

Meerkin³

et al. 2013

Lymphatic Research and Biology

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“…Women have a higher fat mass ratio than men, and less muscle mass, and their different fat distribution and consequently different center of gravity also make it easier for women to fall. [35][36][37] Analyzing our data for each SPPB item, lower gait speed, however modest, seemed to be the most sensitive factor for pinpointing recurrent fallers among women, followed by the tandem test and the five timed chair stands. Our findings are supported by other work reporting a significant difference in gait speed between fallers and non-fallers.…”

Section: Discussionmentioning

confidence: 99%

Association Between Short Physical Performance Battery and Falls in Older People: The Progetto Veneto Anziani Study

Veronese

Bolzetta

Toffanello

et al. 2014

Rejuvenation Research

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113

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It is known that weakness in the lower limbs is associated with recurrent falls in old people. Among the tests routinely used to assess lower extremity strength, the Short Physical Performance Battery (SPPB) is one of those used most often, but its relationship with recurrent falls is poorly investigated. We aimed to determine if SPPB scores are related to recurrent falling in a sample of 2710 older-aged people, and to ascertain which test in the SPPB is most strongly associated with a higher rate of falls. In this cross-sectional study, we demonstrated that participants scoring 0-6 in the SPPB were more likely to be recurrent fallers than those scoring 10-12 (odds ratio [OR] = 3.46, 95% confidence interval [CI] 2.04-5.88 in women; OR = 3.82, 95% CI 1.77-8.52, in men). SPPB scores of 7-9 were only associated with women being more likely to be recurrent fallers (OR = 2.03, 95% CI 1.28-3.22). When the SPPB items were analyzed separately, even a lower score in gait speed for women was significantly associated with the presence of recurrent falls (OR = 2.11; 95% CI 1.04-4.30), whereas in men only a significant increase in the time taken to complete the five timed chair stands test was associated with a higher rate of falls (OR = 2.75; 95% CI 1.21-6.23). In conclusion, our study demonstrated that SPPB scores £ 6 are associated with a higher fall rate in old people of both genders; in females, even an SPPB score between 7 and 9 identifies subjects at a higher likelihood of being recurrent fallers. Among the single items of the SPPB, the most strongly associated with falls were gait speed in women and the five timed chair stands test in men.

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“…A number of studies have shown that obesity, defined as a body mass index (BMI) ≥ 30 kg/m 2 [31, 32], is associated with low serum 25(OH)D levels [33, 34]. A bidirectional genetic study, which limits confounding, has suggested that higher BMI leads to lower 25(OH)D, each unit increase in BMI being associated with 1.15% lower concentration of 25(OH)D, after adjusting for age, sex, laboratory batch, and month of measurement [35].…”

Section: Vitamin D and Obesitymentioning

confidence: 99%

Vitamin D and Its Relationship with Obesity and Muscle

Cipriani

Pepe

Piemonte

et al. 2014

International Journal of Endocrinology

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The skin synthesis of vitamin D represents the first step of a metabolic pathway whose features have been extensively studied and clarified in the last decades. In particular, the production of active and inactive forms of the hormone and the actions of the corresponding enzymes have offered new insights into the knowledge of vitamin D metabolism. Additionally, the description of the different organs and tissues expressing the vitamin D receptor and its possible functions, as well as its genetic determinants, have allowed focusing on the interrelationship between vitamin D and many physiological and pathological functions. In this context, many studies reported the association between vitamin D and adipose tissue metabolism, as well as the possible role of the hormone in obesity, weight, and fat mass distribution. Finally, many reports focused on the vitamin D-related effects on skeletal muscle, particularly on the mechanisms by which vitamin D could directly affect muscle mass and strength. This paper is mainly aimed to review vitamin D metabolism and its relationship with obesity and skeletal muscle function.

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Limb fat-free mass and fat mass reference values by dual-energy X-ray absorptiometry (DEXA) in a 20–80 year-old italian population

Cited by 71 publications

References 29 publications

Tissue Composition Changes and Secondary Lymphedema

Tissue Composition Changes and Secondary Lymphedema

Association Between Short Physical Performance Battery and Falls in Older People: The Progetto Veneto Anziani Study

Vitamin D and Its Relationship with Obesity and Muscle

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