Likelihood ratio  (razón de verosimilitud): definición y aplicación en Radiología

Fuente-Alba, Claudio Silva; Villagra, Matías Molina

doi:10.1016/j.rard.2016.11.002

Cited by 30 publications

(22 citation statements)

References 6 publications

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“…The range of values and their impact on the clinical utility are: LR+: > 10 great increase, excellent test; 5–10 moderate increase, good test; 2–5: small increase, bad test; <2: minor increase, useless test. LR−: 0.5–1 minor decrease, useless test; 0.2–0.5 small decrease, bad test; 0.1–0.2 moderate decrease, good test; <0.1 great decrease, excellent test [ 3 , 34 , 35 , 36 ]. The confidence interval for all of them was 95%.…”

Section: Methodsmentioning

confidence: 99%

Use of Neurodynamic or Orthopedic Tension Tests for the Diagnosis of Lumbar and Lumbosacral Radiculopathies: Study of the Diagnostic Validity

Monteros

González-Medina

Garrido-Ardila

et al. 2020

IJERPH

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Background: Lumbar radiculopathy is a nerve root disorder whose correct diagnosis is essential. The objective of the present study was to analyze the reliability diagnostic validity of eight neurodynamic and/or orthopedic tension tests using magnetic resonance imaging as the Gold Standard. Methods: An epidemiological study of randomized consecutive cases which was observational, descriptive, transversal, double blinded and was conducted following the Standards for Reporting Diagnostic accuracy studies (STARD) declaration. The sample size was 864 participants. Internal and external validity (CI = 95%) and reliability, were calculated for all tests performed independently. The diagnostic validity of the combined and multiple tests in parallel was also calculated. Results: The analysis indicated that only two tests performed independently had external validity, but neither had reliability or precision. The Straight Leg Raise test and the Bragard test performed in a multiple parallel way showed high sensitivity (97.40%), high negative predictive value (PV− 96.64%) and external validity (Likelihood Ratio− 0.05). The combined test of the Slump test and the Dejerine’s triad had internal and external validity. Conclusions: The Straight Leg Raise test and the Bragard test performed in a multiple parallel way and the combined test of the Slump Test and the Dejerine’s triad have clinical validity to discard lumbar or lumbar-sacral radiculopathy.

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Section: Methodsmentioning

confidence: 99%

Use of Neurodynamic or Orthopedic Tension Tests for the Diagnosis of Lumbar and Lumbosacral Radiculopathies: Study of the Diagnostic Validity

Monteros

González-Medina

Garrido-Ardila

et al. 2020

IJERPH

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“…Por el contrario, LR < 1 disminuyen la probabilidad de que el trastorno esté presente, a menor el LR, mayor es la disminución de la probabilidad. En este caso, aunque los valores de LR hallados por sí solo parecen indicar cambios modestos en la probabilidad posprueba, su contribución a la práctica clínica puede ser importante si se la utiliza en forma combinada con una correcta valoración clínica, incluyendo evaluación de factores de riesgo y examen clínico (29) .…”

Section: Discussionunclassified

Validación de un instrumento para la pesquisa de problemas del desarrollo en menores de 5 años en Uruguay

Larraz

Ferrero

Roca³

et al. 2020

RMU

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Introducción: la detección temprana de problemas del desarrollo en niños permite aplicar intervenciones oportunas que mejoran el pronóstico y disminuyen la discapacidad. Esto requiere aplicar pruebas de pesquisa sensibles, sencillas y de bajo costo. Con este propósito, en Uruguay se desarrolló la Guía Nacional para la Vigilancia del desarrollo del Niño y la Niña menores de 5 años versión 2 (GNVD V2). Su utilización requiere conocer las propiedades psicométricas e índices fijos y variables. Objetivo: validación concurrente de la GNVD V2 frente al Inventario de Desarrollo Battelle 4ª edición. Método: se realizó un estudio transversal, observacional, en una muestra representativa de niños de 1 mes a 5 años de centros educativos de Montevideo. Se relacionaron los resultados de la aplicación de la GNVD V2 con los del Inventario de Desarrollo Battelle 4ª edición. Se calculó la sensibilidad, especificidad, valores predictivos positivo y negativo de la GNVD V2, según diferentes puntos de corte. Se estimó el beneficio clínico de su aplicación mediante las razones de verosimilitud o likelihood ratios. Se realizó análisis psicométrico. Resultados: la validación se realizó con 341 niños. No haber fallado en ninguna de las 12 conductas ubicadas a la izquierda de las cuatro áreas correspondientes a su edad presenta sensibilidad 77%, especificidad 65%, valor predictivo positivo 42% y valor predictivo negativo 89%. Con dicho punto de corte, el LR (+) es 2,2 y el LR (-) 0,35 y la probabilidad de presentar un trastorno cuando no pasa la prueba 1,6 y cuando la pasa 0,26. Conclusiones: la GNVD V2 posee propiedades psicométricas adecuadas e índices fijos similares a tests validados a nivel internacional que permiten recomendarlo como instrumento nacional de pesquisa.

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“…By risk estimators, it is possible to know the aspects related to the incidence that lead to the evaluation of the clinical relevance in the mentioned event [23][24][25].…”

Section: Discussionmentioning

confidence: 99%

Clinical relevance linked to echocardiography diagnosis in Bland, White and Garland syndrome

Almira¹,

Morejón²,

Ricardo³

et al. 2020

J Cardiol Cardiovasc Med

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Introduction: Bland, White and Garland syndrome is a coronary anomaly with high mortality without treatment. Its clinical presentation is varied which makes epidemiological documentation diffi cult. Echocardiography is a useful non-invasive tool for diagnosis. Objective: To determine the echocardiographic variables that lead to the diagnosis of Bland, White and Garland syndrome and their clinical relevance. Material: Observational, prospective and cross-sectional study in 31 patients of the "William Soler" Pediatric Cardiocenter, from 2005 to 2018. To check the association of echocardiographic variables with the diagnosis of Bland, White and Garland syndrome, an effectiveness study was carried out that included the analysis of the incidence of echocardiographic variables that lead to the diagnosis of this entity. The clinical relevance was estimated according to the minimum importance limit. The statistical validation of the research results adopted a signifi cance level of less than 5% (p < 0.05). Results: The variables that facilitate the echocardiographic diagnosis of Bland, White and Garland syndrome were the echocardiographic visualization of the anomalous connection and the reversed fl ow in the anomalous left coronary artery. These echocardiographic measures have clinical relevance according to the quantifi cation of risk estimators (incidence) the echocardiographic visualization of the anomalous connection, RR 39.00 and the reversed fl ow in the anomalous coronary artery, RR 26.31. LIM´s calculation value amounted to 6.31 and coincided with the risk estimators (incidence). Conclusion: The echocardiographic visualization of the anomalous origin of the left coronary artery from the pulmonary arterial trunk and the detection of the local intracoronary reversed fl ow instituted as factors to be considered for the effective diagnosis of the disease. The documentation of the diagnostic aspects of the syndrome through echocardiography contains high statistical value and clinical relevance.

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Likelihood ratio (razón de verosimilitud): definición y aplicación en Radiología

Cited by 30 publications

References 6 publications

Use of Neurodynamic or Orthopedic Tension Tests for the Diagnosis of Lumbar and Lumbosacral Radiculopathies: Study of the Diagnostic Validity

Use of Neurodynamic or Orthopedic Tension Tests for the Diagnosis of Lumbar and Lumbosacral Radiculopathies: Study of the Diagnostic Validity

Validación de un instrumento para la pesquisa de problemas del desarrollo en menores de 5 años en Uruguay

Clinical relevance linked to echocardiography diagnosis in Bland, White and Garland syndrome

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