Lignans from the Fruits ofForsythia suspensa(Thunb.) Vahl Protect High-Density Lipoprotein during Oxidative Stress

Simultaneous Separation of Eight Lignans in Forsythia suspensa by β-Cyclodextrin-Modified Capillary Zone Electrophoresis

“…A number of biological activities of these compounds were previously reported [1,2]. The phillyrin, phillygenin, pinoresinol-4- O -β-glucoside were selected to be quantitative constituents in F. suspensa extract in the 2010 and 2015 editions of Chinese Pharmacopoeia.…”

“…The fruits of F. suspensa have been used as a traditional Chinese medicine for centuries, named ‘Lianqiao’ in Chinese, which has long been used to treat gonorrhea, erysipedas, inflammation, pharyngitis, pyrexia, tonsillitis, ulcers and other diseases. In recent years, reports about the benefits of F. suspensa lignans have dramatically increased [1,2]. The ‘Lianqiao’ could be classified into ‘Qingqiao’ and ‘Laoqiao’ according to the maturity levels of the fruits of F. suspensa .…”

Distribution Patterns for Bioactive Constituents in Pericarp, Stalk and Seed of Forsythiae Fructus

“…Chlorogenic acid (2) was received from Baoji Herbest Bio-Tech Co., Ltd. (Baoji, China). Caffeic acid (3), galuteolin (9), quercetin (13), and kaempferol (19) were provided by National Institutes for Food and Drug Control (Beijing, China). Forsythoside B (4), forsythoside I (5), forsythiaside A (8), (+)-phillyrin (16), and (+)-pinoresinol (20) were bought from Liangwei Bio-technology Co., Ltd. (Nanjing, China).…”

“…Hitherto, approximately 210 compounds have been reported from FF, including phenylethanoid glycosides, lignans, flavonoids, phenolic acids, terpenoids, cyclohexylethanol derivatives, and so on [4]. Among them, the first four types of compounds were demonstrated to be responsible for the diverse biological activities of the herbal medicine, such as antibacterial [5][6][7], anti-inflammatory [8,9], antiviral [10,11], antioxidant [12,13], anti-endotoxin [14], and hepatoprotective [15,16]. Previous studies have intensively described the effects of ecological environment [17,18], harvesting time [19], and processing methods [20] on the formation and accumulation of bioactive metabolites in FF, in virtue of chromatographic fingerprint techniques or absolute quantitative methods.…”

Comprehensive metabolomics analysis based on UPLC-Q/TOF-MSEand the anti-COPD effect of different parts ofCelastrus orbiculatusThunb.

“…The markers in stem including 4 triterpenoids (64, 84, 85, 100), 1 avonoids (2), 1 phenylpropanoids (30), 1 steroids (52) and 1 organic acid esters (61). The markers in leaf including 3 sesquiterpenoids (11,40,117), 1 avonoids (14) and 1 triterpenoids (54). Additionally, among these potential chemical markers, the contents of 57 and 88 in root, 52 in stem, 40, 54 and 117 in leaf were much higher than in the other two parts (p < Fig.…”