Light Scattering by Pigment Epithelium Granules in the Human Retina

Bülow, Niels

doi:10.1111/j.1755-3768.1968.tb05897.x

Cited by 13 publications

(1 citation statement)

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“…Scattering takes place at the pixment granules. This was concluded by Biilow (1968) from the interference pattern he observed under the microscope. Thus, the high scattering coefficients we measured corresponded to the density and the size of the retinal pigment granules, which are at 0.5-1 p m (Ham 1975) about ten times larger than melanin granules in other pigmented human tissues (Drocbmans 1966).…”

Section: The Retinal Pigment Epithelium (Rpe)mentioning

confidence: 87%

Optical properties of ocular fundus tissues-an in vitro study using the double-integrating-sphere technique and inverse Monte Carlo simulation

et al. 1995

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Various models have been published calculating the light transport at the ocular fundus either for interpretation of in vivo reflectance measurements or for the prediction of photocoagulation effects. All these models took the absorption spectra of the pigments located at the ocular fundus, melanin, haemoglobin, xanthophyll, and the photoreceptor pigments, into account. However, light scattering inside the single fundus layers has not been investigated in detail and was, therefore, neglected in the calculations or only considered by very rough approximations. This paper presents measurements on specimens of retina, retinal pigment epithelium, choroid, and sclera using the double-integrating-sphere technique. Absorption coefficients, scattering coefficients, and anisotropy of scattering were calculated by an inverse Monte Carlo simulation from the measured collimated and diffuse transmittance and diffuse reflectance. Conclusions are drawn for the interpretation of fundus reflectance measurements, which are a useful tool in diagnostics and photocoagulation dosimetry.

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Section: The Retinal Pigment Epithelium (Rpe)mentioning

confidence: 87%