2020
DOI: 10.1002/advs.202000863
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Light‐Responsive Inorganic Biomaterials for Biomedical Applications

Abstract: Light‐responsive inorganic biomaterials are an emerging class of materials used for developing noninvasive, noncontact, precise, and controllable medical devices in a wide range of biomedical applications, including photothermal therapy, photodynamic therapy, drug delivery, and regenerative medicine. Herein, a range of biomaterials is discussed, including carbon‐based nanomaterials, gold nanoparticles, graphite carbon nitride, transition metal dichalcogenides, and up‐conversion nanoparticles that are used in t… Show more

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Cited by 189 publications
(154 citation statements)
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“…[111] The later materials are of particular interest because the metallic propellant is degraded after use, leaving nontoxic byproducts behind. [112] Optical [113][114][115][116][117][118][119] and electrical fields [120][121][122][123][124][125] have also been used to enhance the reaction rate of catalytic materials to produce locomotion, although they are less commonly used in biomedical applications.…”
Section: Robotics Engines At Small Scalesmentioning
confidence: 99%
“…[111] The later materials are of particular interest because the metallic propellant is degraded after use, leaving nontoxic byproducts behind. [112] Optical [113][114][115][116][117][118][119] and electrical fields [120][121][122][123][124][125] have also been used to enhance the reaction rate of catalytic materials to produce locomotion, although they are less commonly used in biomedical applications.…”
Section: Robotics Engines At Small Scalesmentioning
confidence: 99%
“…Internal physical stimuli may include mechanical stress, surface topography, and surface charge, while external physical stimuli comprise light, temperature, electrical and magnetic fields. 37,38 For example, piezoelectric films (PVDF) are activated by external cyclic loading to form calcium phosphate minerals. 39 Exposure of osteoblastic cells (MC3T3-E1) to an electric field can produce TGF-β through the calcium/calmodulin pathway for cell proliferation, differentiation, and extracellular matrix (ECM) synthesis leading to transient inflammation and tissue repair.…”
Section: Bone Research (2021) 9:12mentioning
confidence: 99%
“…Due to their fine-tunable properties, metallic/inorganic NPs have been widely investigated for diagnosis and/or therapy of various diseases (e.g., cancer [ 69 ], infectious diseases [ 70 ], inflammatory diseases [ 71 ], and wound care [ 72 ]), including gold NPs (AuNPs), silver NPs (AgNPs), copper NPs (CuNPs), metal oxides NPs, graphene oxide-based NPs, and mesoporous silica (mSiO 2 ) NPs, etc . [ 73 , 74 ]. Due to their high surface area-to-volume ratios and fine-tunable surface engineering, metallic/inorganic NPs, especially the metal NPs, can immobilize and sufficiently display diagnostic molecules, thus achieving signal amplification and improvements in sensitivity of molecular detection [ 75 ].…”
Section: Rationality Of Nanoplatforms In Sepsis Managementmentioning
confidence: 99%
“…Metallic/inorganic NPs also show considerable superiorities as delivery platforms, including high drug loading capability, biotunable targeted properties, long circulation, on-demand release, and low immunogenicity, etc . [ 74 ]. Integrating multiple types of metallic/inorganic NPs into one unit enables synergistic enhancement in rational drug delivery, and consequently overcomes the limitations of conventional drug delivery platforms.…”
Section: Rationality Of Nanoplatforms In Sepsis Managementmentioning
confidence: 99%