Light-Emitting Diode-Assisted Narrow Band Imaging Video Endoscopy System in Head and Neck Cancer

Abstract

Background/AimsTo validate the effectiveness of a newly developed light-emitting diode (LED)-narrow band imaging (NBI) system for detecting early malignant tumors in the oral cavity.MethodsSix men (mean age, 51.5 years) with early oral mucosa lesions were screened using both the conventional white light and LED-NBI systems.ResultsSmall elevated or ulcerative lesions were found under the white light view, and typical scattered brown spots were identified after shifting to the LED-NBI view for all six patients. Histopathological examination confirmed squamous cell carcinoma. The clinical stage was early malignant lesions (T1), and the patients underwent wide excision for primary cancer. This is the pilot study documenting the utility of a new LED-NBI system as an adjunctive technique to detect early oral cancer using the diagnostic criterion of the presence of typical scattered brown spots in six high-risk patients.ConclusionsAlthough large-scale screening programs should be established to further verify the accuracy of this technology, its lower power consumption, lower heat emission, and higher luminous efficiency appear promising for future clinical applications.

Experimental Evaluation and Analysis of LED Illumination Source for Endoscopy Imaging

“…According to the NBI system of The Industrial Technology Research Institute of Taiwan, three wavelengths, i.e., Blue, Green, and white, are used in endoscopy. White colour LED allows us to work in bright mode, and endoscope uses typically bright mode [15].…”

LED-Based Light Source Combined with Quantum Dot for Spectral Imaging

“…However, as the xenon lamp produces heat too much, the bulky structure for dissipating heat is needed, and the high maintenance expense is required due to the short lifetime. Recently, applications of the solid state light sources in endoscopy have been reported to substitute the xenon lamp [15]. In particular, the light source with the broad band spectrum induced from phosphor by the blue laser was applied to implement spectral imaging in the clinical study [11].…”

“…In particular, the light source with the broad band spectrum induced from phosphor by the blue laser was applied to implement spectral imaging in the clinical study [11]. Also, the combination of multiple color lightemitting diodes (LEDs) of blue, green, and red was implemented to generate the light of the multispectral band or white light [15,16]. Although LEDs provide the advantages such as high efficiency, low cost, and long lifetime, this approach based on the use of multiple LEDs needs multiple driver modules to supply power to each LED and has a limitation on the expansion to spectral imaging with the lights of more bands.…”