Light-Dissipative and Reprogrammable DNA Hydrogels Enabled by Merocyanine Photoacids

Chemically fueled dynamic switching between assembly-encoded emissions

“…In recent years, the fabrication of dynamic assembly assisted self-abolishing ink with a tunable lifetime for storage and communication encryptions has gained tremendous attention. 29,36,39 To demonstrate transient fluorescent patterning in solution, we developed a pattern or message on the 96 well plate using the amphiphilic assembled solution ( Agg-1 ), which fluoresces cyan, as shown in Fig. 4c.…”

“…In this context, programming supramolecular luminescent properties is attaining considerable research interest owing to its wide scope of applications in fluorescent imaging, sensors, displays and information storage, encryption and many more. 33–36 The supramolecular approach relies on exploiting different noncovalent intermolecular interactions to tune the emissive properties of the systems. Tang and co-workers pioneered the aggregation-induced emission (AIE) properties of certain fluorophores called AIEgens, whose aggregates emit more strongly than monomers, thereby opening up vast opportunities to develop a new class of luminescent materials.…”

Light Responsive DNA Nanomaterials and Their Biomedical Applications

“…Later, the open state can efficiently come back to the closed form by Vis irradiation (Figure 2b). [55][56][57][58][59] Rizzuto and coworkers developed this spiroyran derivative into a light-activated pHmodulator for dynamic assembly/disassembly of micron-length DNA origami fibrils. [60] A non-canonical DNA-DNA interaction between poly A DNA overhangs was employed to connect the DNA origami tiles together with the assistance of protons, which can be released from the light-activated pH-modulator.…”