Ligand Influences in Copper-Dioxygen Complex-Formation and Substrate Oxidations

“Green” Atom Transfer Radical Polymerization: From Process Design to Preparation of Well-Defined Environmentally Friendly Polymeric Materials

“…The electrochemical behavior of many Cu I complexes with multidentate N-containing ligands has been studied in relation to oxygen binding by the metal center. 230 It was found that subtle changes in the ligand substituents can have a dramatic effect on the redox properties of the complexes (changes in the E 1/2 values by more than 100 mV). Some of the studied ligands are presented in Figure 9, and the measured redox potentials of their copper complexes are summarized in Table 2.…”

Theoretical Characterization of End-On and Side-On Peroxide Coordination in Ligated Cu2O2 Models

“…[1][2][3][4][5][6][7][8] Tyrosinase 1,5,6,9 is one example of an enzyme whose active site incorporates a Cu 2 O 2 core, and substantial effort has also been devoted to the characterization of smaller inorganic models characterized by the same core. 2, [10][11][12][13][14][15][16][17][18] There are several motifs for the binding of molecular O 2 to two supported copper(I) atoms ( Figure 1). 12,19 Best characterized experimentally (because they have been observed for many different supporting ligand sets) are the side-on µ-η 2 :η 2 peroxo and the bis(µ-oxo).…”

Katalytische Phenolhydroxylierung mit Sauerstoff: Substratvielfalt jenseits der Proteinmatrix von Tyrosinase

“…Angesichts der Geschicklichkeit der Natur bei der Ausführung katalytischer Monooxygenase-Reaktionen mit Disauerstoff [6][7][8][9] ist der intellektuelle Aufwand einer Übertra-gung des katalytischen Mechanismus vom aktiven Zentrum auf ein synthetisches System allerdings gerechtfertigt. Des Weiteren sind Synthesechemiker bisher auf eher exotische Reagentien für Sauerstoffatom-Insertionen angewiesen.…”