Lifetime Weight Course as a Phenotypic Marker of Severity and Therapeutic Response in Patients with Eating Disorders

Agüera, Zaida; Vintró-Alcáraz, Cristina; Baenas, Isabel; Granero, Roser; Sánchez, Isabel; Sánchez‐González, Jéssica; Menchón, José M.; Jiménez‐Murcia, Susana; Treasure, Janet; Fernández‐Aranda, Fernando

doi:10.3390/nu13062034

Cited by 6 publications

(4 citation statements)

References 58 publications

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“…The typical characteristics of BN and binge-eating disorder (BED) are recurrent BE episodes, defined as losing control over eating amounts of food that are objectively large. While attempts to prevent weight gain through inappropriate compensatory behaviors such as self-induced vomiting is characteristic of BN, BED does not share this characteristic [40,41].…”

Section: Links Between Obesity and Edsmentioning

confidence: 99%

Obesity and Eating Disorders in Children and Adolescents: The Bidirectional Link

et al. 2021

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Obesity, eating disorders and unhealthy dieting practices among children and adolescents are alarming health concerns due to their high prevalence and adverse effects on physical and psychosocial health. We present the evidence that eating disorders and obesity can be managed or prevented using the same interventions in the pediatric age. In the presence of obesity in the pediatric age, disordered eating behaviors are highly prevalent, increasing the risk of developing eating disorders. The most frequently observed in subjects with obesity are bulimia nervosa and binge-eating disorders, both of which are characterized by abnormal eating or weight-control behaviors. Various are the mechanisms overlying the interaction including environmental and individual ones, and different are the approaches to reduce the consequences. Evidence-based treatments for obesity and eating disorders in childhood include as first line approaches weight loss with nutritional management and lifestyle modification via behavioral psychotherapy, as well as treatment of psychiatric comorbidities if those are not a consequence of the eating disorder. Drugs and bariatric surgery need to be used in extreme cases. Future research is necessary for early detection of risk factors for prevention, more precise elucidation of the mechanisms that underpin these problems and, finally, in the cases requiring therapeutic intervention, to provide tailored and timely treatment. Collective efforts between the fields are crucial for reducing the factors of health disparity and improving public health.

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Section: Links Between Obesity and Edsmentioning

confidence: 99%

Obesity and Eating Disorders in Children and Adolescents: The Bidirectional Link

et al. 2021

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“…It can be proposed that these people may have an increased risk of developing obesity in adulthood. At least one recent publication showed that people who progress from normal body weight in adolescence to obesity in adulthood were predisposed to an increased risk of developing psychoemotional state disorders but not eating disorders [68].…”

Section: Discussionmentioning

confidence: 99%

Association of Chrononutrition Indices with Anthropometric Parameters, Academic Performance, and Psychoemotional State of Adolescents: A Cross-Sectional Study

Borisenkov,

Tserne,

Popov

et al. 2023

Nutrients

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Adolescents are an at-risk group for circadian misalignment. The contribution of sleep–wake rhythm instability to the psychoemotional, cognitive, and weight disorders of adolescents has been studied in sufficient detail. At the same time, there is insufficient information about the association between chrononutrition indices and the well-being of adolescents. The aim of this study is to investigate the relationship between chrononutrition indices and academic achievement, psychoemotional state, and anthropometric indicators in adolescents. The study involved 12,759 students in grades 6–11 of secondary schools, aged 14.2 ± 1.7 years old; 57.2% of whom were girls. Participants provided personal data, frequency and time of meals during the day and at night, on weekdays and weekends, and completed the Zung Self-Rating Depression Scale and the Yale Food Addiction Scale. There is a U-shaped association between eating mid-phase (EPFc), eating jetlag (EJL), and eating window (EW) with GPA, ZSDSI, and FA. At the same time, the frequency of night eating (NE) is linearly associated with the studied parameters. NE is the strongest predictor of ZSDSI (β = 0.24), FA (β = 0.04), and GPA (β = −0.22). EPFc, EJL, and EW practically do not differ in the strength of their association with the studied indicators. ZSDSI is most closely associated with the chrononutrition indices. There is a weak negative association between BMI and EW (β = −0.03) and NE (β = −0.04). Thus, circadian eating disorders are more often observed in adolescents with poor academic performance, high levels of depression, and food addiction.

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“…Partial remission referred to substantial symptomatic improvement with residual symptoms, while non-remission was used to describe poor outcomes. These categories have been employed to evaluate the efficacy of ED treatments in previous studies [4,[30][31][32]. Treatment discontinuation was classified as dropout, defined as being absent for at least three consecutive therapy sessions.…”

Section: Treatmentmentioning

confidence: 99%

The Role of Food Addiction and Lifetime Substance Use on Eating Disorder Treatment Outcomes

et al. 2023

Self Cite

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Food addiction (FA) and substance use (SU) in eating disorders (ED) have been associated with a more dysfunctional clinical and psychopathological profile. However, their impact on treatment outcomes has been poorly explored. Therefore, this transdiagnostic study is aimed at examining whether the presence of FA and/or SU is associated with treatment outcomes in patients with different ED types. The results were not able to reveal significant differences in treatment outcomes between patients with and without FA and/or SU; however, the effect sizes suggest higher dropout rates in the group with both FA and SU. The predictive models of treatment outcomes showed different features associated with each group. High persistence (i.e., tendency to perseverance and inflexibility) was the personality trait most associated with poor treatment outcomes in patients without addictions. High harm avoidance and younger age at ED onset were the variables most related to poor outcomes in patients with FA or SU. Finally, in the group with both addictive behaviors (FA and SU), the younger patients presented the poorest outcomes. In conclusion, our results suggest that, regardless of presenting addictive behaviors, patients with ED may similarly benefit from treatment. However, it may be important to consider the differential predictors of each group that might guide certain treatment targets.

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Lifetime Weight Course as a Phenotypic Marker of Severity and Therapeutic Response in Patients with Eating Disorders

Cited by 6 publications

References 58 publications

Obesity and Eating Disorders in Children and Adolescents: The Bidirectional Link

Obesity and Eating Disorders in Children and Adolescents: The Bidirectional Link

Association of Chrononutrition Indices with Anthropometric Parameters, Academic Performance, and Psychoemotional State of Adolescents: A Cross-Sectional Study

The Role of Food Addiction and Lifetime Substance Use on Eating Disorder Treatment Outcomes

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