Lifetime prevalence of self-reported atopic diseases in a population-based sample of elderly subjects: results of the ESTHER study

Wolkewitz, Martin; Rothenbacher, Dietrich; Löw, Michael; Stegmaier, Christa; Ziegler, H; Radulescu, Magdalena; Brenner, Hermann; Diepgen, Thomas L.

doi:10.1111/j.1365-2133.2006.07659.x

Cited by 72 publications

(61 citation statements)

References 18 publications

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“…Similar to other atopic diseases, the incidence of AD is gradually increasing in countries with aging populations [3,4,5]. The prevalence of AD in our 6,511 analyzed subjects was 1.86%, which agrees with other published data [3,4].…”

Section: Discussionsupporting

confidence: 81%

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Clinical Features and Immunological Markers of Atopic Dermatitis in Elderly Patients

Bożek¹,

Fisher²,

Filipowska³

et al. 2011

Int Arch Allergy Immunol

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Background: Atopic dermatitis (AD) is increasing among the elderly. Staphylococcus aureus colonization is one of the most important aggravating factors in AD. Objective: This study analyses the clinical features of AD in elderly patients and determines the pathogenic roles of staphylococcal superantigens in AD with low and high total IgE levels. Methods:S. aureus enterotoxin genes were evaluated using PCR. Additionally, S. aureus-specific IgE levels and peripheral blood lymphocyte profiles were assessed. Results: A total of 44 women and 77 men diagnosed with AD with a mean age of 68.92 ± 6.51 years were evaluated. In 17 (68%) patients with AD and low levels of total IgE, there was a positive correlation between the positive results for enterotoxin B, S. aureus-specific IgE antibodies and Th1 cytokine profiles (Spearman’s rank correlation test, r = 0.89, p < 0.05). Conclusion: Our results indicate that AD patients with low total IgE levels differ in immunopathogenesis from AD patients with high circulating levels of total IgE AD.

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Section: Discussionsupporting

confidence: 81%

“…AD is much less common in adults, especially in the elderly. The prevalence of AD in patients who are 50 years of age or older is estimated to range from 1.5 to 10%; however, different forms of dermatitis exist and some may be caused by IgE reactions [1,2,3,4]. …”

Section: Introductionmentioning

confidence: 99%

Clinical Features and Immunological Markers of Atopic Dermatitis in Elderly Patients

Bożek¹,

Fisher²,

Filipowska³

et al. 2011

Int Arch Allergy Immunol

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“…However, the prevalences of atopic eczema (1.4%) and of acne vulgaris (4.2%) are lower than postulated in the few epidemiological studies [4, 9]. …”

Section: Discussionmentioning

confidence: 94%

“…Thus far, there have been only a few population-based studies of skin diseases so that the available knowledge on the epidemiology of skin diseases is based essentially on studies of selective patient collectives. Correspondingly, the figures on the prevalence of skin diseases vary considerably, for example for psoriasis vulgaris between 1.5 and 2.5% [1], for atopic eczema between 1.5 and 4% in adults and between 4 and 15% in children [2,3,4] and for hand eczema between 1 and 4% in the normal population and between 4.6 and 18% in occupational risk groups [5, 6]. An Italian screening study revealed a prevalence of congenital melanocytic nevi of 0.67% in young men [7].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Skin Diseases in a Cohort of 48,665 Employees in Germany

Schaefer¹,

Rustenbach²,

Zimmer³

et al. 2008

Dermatology

157

110

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Background: Epidemiological data are important for planning medical care. Thus far, only few prevalence data for skin diseases have been published in Germany, most of them not population based. Objectives: Estimation of prevalences of common skin diseases in a sample of employees of German companies. Methods: Whole-body examinations were performed by trained dermatologists in 150 companies as part of skin cancer screenings. Using a standardized and computerized data entry, all clinical dermatological findings were documented. Explicitly skin lesions requiring current treatment were noted. The retrospective evaluation of the data was descriptive, using the diagnoses defined a priori in the data entry mask. Results: 48,665 persons (52.8% male) with a mean age of 43.2 years were examined. The following frequencies of chronic and acute inflammatory skin diseases were observed: contact eczema 8.9%, acne 4.2%, seborrhoeic eczema 3.4%, rosacea 2.2%, psoriasis vulgaris 2.1%, atopic eczema 1.4% and lichen ruber 0.07%. In total, dermatological findings needing treatment were observed in 19% of the study cohort; 1.3% of the participants presented a suspicious finding requiring diagnostics for skin malignoma. Conclusions: There is a high frequency of chronic inflammatory skin diseases in the general working population and a high need for dermatological treatment.

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“…One study shows that the prevalence of AD in adult and elderly is 1% to 3% [8]. In other study, the prevalence of AD in >50 years old patients is 1.5% to 10% [9].…”

Section: Introductionmentioning

confidence: 99%

Senile Atopic Dermatitis Patients’ Profile in Geriatric Outpatient Clinic Dermatovenereology Department Cipto Mangunkusumo Hospital in 2011-2015

Legiawati¹,

Yusharyahya²,

Bianti³

2017

J Clin Exp Dermatol Res

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Background and objective: As the life expectancy increases, diseases in the elderly also increase. Senile atopic dermatitis is atopic dermatitis (AD) which persists until elderly or the onset first occurs in elderly. The prevalence of senile AD remains unclear and in Indonesia, there have not been any study regarding senile AD yet. Therefore, it is needed to conduct a study regarding this topic in geriatric outpatient clinic Dermatovenereology Department, Cipto Mangunkusumo Hospital in 2011-2015.

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Lifetime prevalence of self-reported atopic diseases in a population-based sample of elderly subjects: results of the ESTHER study

Abstract: The lifetime prevalence of AD is considerably lower in the elderly compared with the prevalence reported among younger adults in recent studies. Adults with a longer duration of school education appeared to have a higher risk for atopic diseases.

Cited by 72 publications

References 18 publications

Clinical Features and Immunological Markers of Atopic Dermatitis in Elderly Patients

Clinical Features and Immunological Markers of Atopic Dermatitis in Elderly Patients

Prevalence of Skin Diseases in a Cohort of 48,665 Employees in Germany

Senile Atopic Dermatitis Patients’ Profile in Geriatric Outpatient Clinic Dermatovenereology Department Cipto Mangunkusumo Hospital in 2011-2015

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