Lifestyle Modification in the Management of Obesity

Adverse effects of weight loss: Are persistent organic pollutants a potential culprit?

“…There is extensive evidence to suggest that weight loss improves cardiometabolic risk factors and, in turn, may reduce the risk of type 2 diabetes and cardiovascular diseases [55][56][57][58][59]. For example, bariatric surgery appears to maintain its positive effects on several cardiometabolic risk factors over a 10-year period.…”

Bariatric Surgery versus Lifestyle Interventions for Morbid Obesity—Changes in Body Weight, Risk Factors and Comorbidities at 1 Year

“…Although conservative treatments of obesity can result in short-term weight loss of approximately 10% body weight, this is usually not sustained in the longterm [6]. This has led some to consider bariatric surgery as the only sustainable treatment for morbid obesity [7].…”

Mechanisms of bariatric surgery and implications for the development of endoluminal therapies for obesity

“…10-19 Furthermore, most of these results occurred as part of structured research studies or in academic centers, which limited their generalizability to the community. [10][11][12][13][14][15][16][17][18][19] The recidivism after cessation of therapy, weight regain, and the need for intensive monitoring and therapy during treatment limit Abbreviations: AGB, adjustable gastric band; BPD, biliopancreatic diversion; BPD/DS, biliopancreatic diversion with duodenal switch; JIB, jejunoileal bypass; PYY, peptide Y-Y; RYGB, Roux-en-Y gastric bypass; SG, sleeve gastrectomy; VBG, vertical banded gastroplasty. …”