Lifestyle Modification Decreases Arterial Stiffness in Overweight and Obese Men: Dietary Modification vs. Exercise Training

Maeda, Seiji; Zempo-Miyaki, Asako; Sasai, Hiroyuki; Tsujimoto, Takehiko; So, Rina; Tanaka, Kiyoji

doi:10.1123/ijsnem.2013-0107

Cited by 29 publications

(18 citation statements)

References 23 publications

(42 reference statements)

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“…Our study also found that essential hypertension had different effects on bone mineral density at different sites. The mechanism may be that ① different parts of body differ in skeletal muscle strength and exhibit inconsistent activity, which leads to varied effects on bone mineral density at different sites [ 38 – 40 ]. Ward's triangle is primarily composed of cancellous bone, has a local blood supply that is poor, and is prone to fracture; therefore, Ward's triangle is a sensitive region for detecting bone mineral density.…”

Section: Discussionmentioning

confidence: 99%

Association between essential hypertension and bone mineral density: a systematic review and meta-analysis

Lü

Liu

2017

Oncotarget

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BackgroundWe conducted this systematic review and meta-analysis to evaluate the association between essential hypertension (EH) and bone mineral density (BMD).Results17 articles were included in our meta-analysis, with a total of 39,491 patients. Of these, 13,375 were patients with EH and 26,116 were patients without EH. Meta-analysis results showed that EH can reduce the BMD of the lumbar spine (95% CI: −0.08∼0.01, P=0.006), femoral neck (95% CI: −0.09∼-0.02, p = 0.001), ward's triangle (95% CI: −0.45∼-0.25, p=0.000), femoral intertrochanteric (95% CI: −0.90∼-0.64, p = 0.000), calcaneus (95% CI: −0.31∼-0.18, p = 0.000) and distal forearm (95% CI: −0.09∼-0.03, p = 0.000), but EH cannot reduce the BMD of the femur rotor (95% CI: −0.07∼0.24, p = 0.273). Subgroup analysis showed that EH can reduce the BMD of the lumbar spine (95% CI: −0.11∼-0.03, p = 0.000) and femoral neck (95% CI: −0.11∼-0.07, p = 0.000) in Asian populations. In non-Asian populations, EH can reduce the BMD of the femoral neck (95% CI: 0.04∼0.19, p = 0.002), but cannot reduce the BMD of the lumbar spine (95% CI: −0.04∼0.11, p = 0.346).Materials and MethodsWe conducted a systematic review of the published literature on the association of EH and BMD by searching the Cochrane Library, PubMed, EMBASE, CBM, CNKI and VIP databases inception to October 2016. Stata 11.0 software was used for data analysis.ConclusionsOur meta-analysis suggests that EH can reduce the BMD of the human body, and for different parts of the bone, the degree of reduction is different. In addition, for different regions and populations, the reduction level of BMD is inconsistent.

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Section: Discussionmentioning

confidence: 99%

Association between essential hypertension and bone mineral density: a systematic review and meta-analysis

Lü

Liu

2017

Oncotarget

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“…Therefore, it is important for obese individuals to commit to losing weight before developing such diseases. We previously reported that lifestyle modification, consisting of dietary modification and habitual aerobic exercise training, is effective for weight loss and lowering the risk of cardiovascular diseases in obese individuals 7) .…”

Section: Introductionmentioning

confidence: 99%

Changes in plasma amino acid concentrations in overweight and obese men after weight loss program including dietary modification and aerobic exercise

Myoenzono

Yoshikawa

Kumagai

et al. 2020

JPFSM

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Obesity causes lifestyle diseases that increase one's mortality risk. Studies have demonstrated that plasma amino acid concentrations may be useful for screening several lifestyle-related diseases. This study aimed to investigate the effects of weight loss using dietary modification and aerobic exercise training on plasma amino acid concentrations in overweight and obese men. Thirty-two overweight or obese men (age, 49 ± 2 years; body mass index, 29.2 ± 0.3 kg/m 2) completed a 12-week intervention consisting of dietary modification (group lectures and individual counseling 8 times over 12 weeks; 1680 kcal/day) and aerobic exercise training (90 min/day, 3 times weekly, 60-80% maximum heart rate). Before and after 12 weeks, body mass index, energy intake, physical activity, and plasma concentrations for 39 kinds of amino acids were measured. The 12-week lifestyle modification led to successful weight loss (-12.6 kg). Total energy intake significantly decreased, while peak oxygen uptake, physical activity and step count significantly increased after the 12-week lifestyle modification. Plasma concentrations for 6 kinds of amino acids were significantly increased, while those for 9 kinds of amino acids were significantly decreased after the 12-week lifestyle modification. Our findings suggest that the lifestyle intervention consisting of dietary modification and aerobic exercise training significantly changes plasma concentrations of several kinds of amino acids in overweight and obese men.

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“…CAVI changes over a short period of time in response to alterations in circulatory conditions; it is sensitive to subclinical changes in major arteries before impairment and it can be a reliable indicator of treatment effectiveness or modification in lifestyle [ 34 ]. Healthy lifestyle, physical exercise and smoking cessation, for example, prevent and treat early vascular aging [ 35 , 36 ].…”

Section: Discussionmentioning

confidence: 99%

Dark chocolate and reduced snack consumption in mildly hypertensive adults: an intervention study

Koli

Köhler

Tonteri

et al. 2015

Nutr J

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BackgroundSeveral studies have shown that cocoa and cocoa-containing foods have the potential to lower blood pressure and improve endothelial function. Most of the studies reporting the beneficial effects of dark chocolate on blood pressure have been short (≤ 4 weeks). The aim of the present 8-wks (weeks) study was to assess the effects of regular consumption of dark chocolate during a reduced snack consumption intervention on blood pressure and other cardiovascular risk factors in mildly hypertensive individuals.DesignThis was a randomized, controlled, cross-over trial involving 22 adults (8 women, 14 men), aged 33–64 y, BMI 27.7 ± 3.7 kg/m2 with mild hypertension. During the intervention period (8-wks) the participants reduced the intake of habitual snacks and replaced them with dark chocolate (49 g/day). In the control period, they only reduced the snacks without any added chocolate. Data (blood lipid profile, glucose, insulin, 24 h blood pressure) was collected in the beginning and end of both periods (intervention and control), and some variables also in the run-in and run-out periods (weight, body fat percentage, blood pressure, arterial stiffness index, diet and physical activity).ResultsDaily consumption of dark chocolate had no effects on 24 h blood pressure, resting blood pressure (mean ± SD, pre 142 ± 11.5/89 ± 8.4 mmHg vs. post 142 ± 14.2/88 ± 9.4 mmHg in systolic and diastolic blood pressure, respectively) or arterial stiffness (mean ± SD, pre 7.68 ± 0.88 vs. post 7.76 ± 0.89).Weight was reduced by 1.0 ± 2.2 kg during the control (reduced snack only) period, but was unchanged while eating chocolate (p < 0.027 between the treatments).ConclusionThe data collected in this study indicates that inclusion of dark chocolate daily in the diet had no significant effects on blood pressure or other cardiovascular risk factors during a reduced snack period.Trial registrationClinicalTrials.gov identifier NCT02130141

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Lifestyle Modification Decreases Arterial Stiffness in Overweight and Obese Men: Dietary Modification vs. Exercise Training

Cited by 29 publications

References 23 publications

Association between essential hypertension and bone mineral density: a systematic review and meta-analysis

Association between essential hypertension and bone mineral density: a systematic review and meta-analysis

Changes in plasma amino acid concentrations in overweight and obese men after weight loss program including dietary modification and aerobic exercise

Dark chocolate and reduced snack consumption in mildly hypertensive adults: an intervention study

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