Lifestyle intervention to prevent diabetes in men and women with impaired glucose tolerance is cost-effective

Lindgren, Peter; Lindström, Jaana; Tuomilehto, Jaakko; Uusitupa, Matti; Peltonen, Markku; Jönsson, Bengt; Fairé, Ulf dé; Hellénius, Mai-Lis

doi:10.1017/s0266462307070286

Cited by 82 publications

(86 citation statements)

References 26 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some studies have suggested that preventing diabetes, like preventing some other chronic diseases, would increase medical costs in part because of increased life spans. Other studies (9)(10)(11)(12) have found that diabetes prevention would lead to substantial long-term cost savings, despite the extended life expectancy. To assess the cost implications of diabetes prevention, it is crucial to know lifetime medical costs for people with diabetes relative to those of people without diabetes.…”

mentioning

confidence: 99%

The Lifetime Cost of Diabetes and Its Implications for Diabetes Prevention

et al. 2014

View full text Add to dashboard Cite

OBJECTIVE To assess the cost implications of diabetes prevention, it is important to know the lifetime medical cost of people with diabetes relative to those without. We derived such estimates using data representative of the U.S. national population. RESEARCH DESIGN AND METHODS We aggregated annual medical expenditures from the age of diabetes diagnosis to death to determine lifetime medical expenditure. Annual medical expenditures were estimated by sex, age at diagnosis, and diabetes duration using data from 2006–2009 Medical Expenditure Panel Surveys, which were linked to data from 2005–2008 National Health Interview Surveys. We combined survival data from published studies with the estimated annual expenditures to calculate lifetime spending. We then compared lifetime spending for people with diabetes with that for those without diabetes. Future spending was discounted at 3% annually. RESULTS The discounted excess lifetime medical spending for people with diabetes was $124,600 ($211,400 if not discounted), $91,200 ($135,600), $53,800 ($70,200), and $35,900 ($43,900) when diagnosed with diabetes at ages 40, 50, 60, and 65 years, respectively. Younger age at diagnosis and female sex were associated with higher levels of lifetime excess medical spending attributed to diabetes. CONCLUSIONS Having diabetes is associated with substantially higher lifetime medical expenditures despite being associated with reduced life expectancy. If prevention costs can be kept sufficiently low, diabetes prevention may lead to a reduction in long-term medical costs.

show abstract

mentioning

confidence: 99%

The Lifetime Cost of Diabetes and Its Implications for Diabetes Prevention

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Modification of lifestyle has shown promise in preventing type 2 diabetes and is cost-effective in high-risk populations (8) …”

Section: Research Design and Methods -People From Four Remotementioning

confidence: 99%

Quantifying the Excess Risk of Type 2 Diabetes by Body Habitus Measurements Among Australian Aborigines Living in Remote Areas

Kondalsamy‐Chennakesavan

Hoy

Wang

et al. 2008

Diabetes Care

View full text Add to dashboard Cite

OBJECTIVE -To quantify the risk for type 2 diabetes by body habitus measurements among remote-living Australian Aborigines relative to that measured in the general Australian population (as characterized by the Australian Diabetes, Obesity and Lifestyle [AusDiab] study).RESEARCH DESIGN AND METHODS -Anthropometric measurements and diabetes status were assessed by standard procedures among Aborigines (n ϭ 1,456) and Australians aged Ն25 years (n ϭ 11,247). Age-adjusted odds ratios (ORs) for diabetes among Aborigines relative to AusDiab participants were calculated by commonly used categories of body size measurements.RESULTS -The OR (95% CI) values for diabetes among normal, overweight, and obese (by waist) Aboriginal women relative to AusDiab women were 2.6 (0.6 -11.5), 13.1 (6.7-25.7), and 6.1 (4.6 -8.0), respectively, and for Aboriginal men relative to AusDiab men, they were 7.6 (4.6 -12.5), 7.6 (4.3-13.4), and 5.2 (3.4 -8.0), respectively. Rates of diabetes were also excessive in Aborigines for each standard category of BMI.CONCLUSIONS -Higher rates of diabetes, even at normal and lower body habitus measurements, among Aborigines suggest that strategies for prevention should expand beyond exclusive focus on diet and weight management.

show abstract

“…However, there is less agreement with respect to the intensive and costly lifestyle intervention of the DPP and DPS [32][33][34]. Although, their results have demonstrated the efficacy of lifestyle modification for diabetes prevention, long-term compliance with these lifestyle changes has proven difficult, however, and the benefits wane with weight regain (Table 2).…”

Section: Translating Diabetes Prevention Trials To the Public Healthmentioning

confidence: 99%

“…The cost-effectiveness of lifestyle interventions has been examined in a number of clinical trials and computer modelling simulations. Although pharmacological interventions have also been shown to prevent diabetes, the cost effectiveness and risk-benefit ratio are less clear [32][33][34][53][54][55][56][57][58][59][60][61][62][63].…”

Section: Cost-effectiveness Of Diabetes Preventionmentioning

confidence: 99%