Lifestyle intervention for gastroesophageal reflux disease: a national multicenter survey of lifestyle factor effects on gastroesophageal reflux disease in China

Yuan, Lingzhi; Yi, Ping; Wang, Gang-Shi; Sheng, T. T.; Huang, Guangming; Qi, Lingzhi; Jia, Yan; Wang, Fen

doi:10.1177/1756284819877788

Cited by 37 publications

(67 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, smoking is also an established risk factor for GERD12. A recent study of 1518 tested subjects 31 has shown that smokers are 1.52 times more likely to develop GERD than non-smokers. However, it is unknown whether smoking cessation reduces the risk of GERD 12 .…”

Section: Discussionmentioning

confidence: 99%

Smoking history and its relationship with comorbidities in patients with obstructive sleep apnea

Shao¹,

Qi²,

Fang³

et al. 2020

Tob. Induc. Dis.

View full text Add to dashboard Cite

INTRODUCTION Current knowledge on the correlation between smoking and comorbidities associated with obstructive sleep apnea (OSA) is limited. This study evaluated the smoking history of OSA patients and analyzed the association between smoking and OSA comorbidities. METHODS Retrospective analysis was performed in newly diagnosed OSA patients in our hospital, a tertiary medical center, from January 2016 to December 2019. In all, 1021 patients were enrolled and divided into two groups, nonsmokers (n=796) and current/former smokers (n=225), in order to compare their clinical manifestations and polysomnographic results and to analyze the association between smoking and comorbidities. RESULTS Compared with the non-smokers, the current/former smokers had higher Epworth sleepiness scale (ESS) scores (9.3 ± 4.0 vs 8.5 ± 5.1; p<0.05), longer sleep latency (SL) [20.5 (12.3-39.3) vs 18.5 (10.0-34.0) minutes; p<0.05], and a lower nocturnal mean oxygen saturation (91.8 ± 3.6% vs 92.8 ± 3.4%; p<0.001). There was no significant difference in the apnea-hypopnea index (AHI) between the two groups. OSA patients with a history of smoking had significantly increased risk of hypertension (OR=2.09; 95% CI: 1.46-3.01), chronic obstructive pulmonary disease (COPD) (OR=9.80; 95% CI: 4.73-20.33), gastroesophageal reflux disease (GERD) (OR=1.97; 95% CI: 1.19-3.27), and chronic pharyngitis (OR=1.83; 95% CI: 1.32-2.54). CONCLUSIONS No significant association was found between previous smoking history and current OSA severity. OSA patients with a history of smoking had an increased risk of hypertension, COPD, GERD, and chronic pharyngitis.

show abstract

Section: Discussionmentioning

confidence: 99%

Smoking history and its relationship with comorbidities in patients with obstructive sleep apnea

Shao¹,

Qi²,

Fang³

et al. 2020

Tob. Induc. Dis.

View full text Add to dashboard Cite

show abstract

“…The etiology of RE is multi-factorial. Lifestyle factors and eating habits such as smoking, drinking, preferences for high-fat and fried foods, and overeating are closely associated with RE [ 3 – 6 ]. In addition, it has been reported in the recent literature that mental disorders, especially anxiety and depression, are closely related to the onset and prognosis of RE [ 7 ], which seriously affects the quality of life of patients.…”

Section: Introductionmentioning

confidence: 99%

Study on the relationship of depression, anxiety, lifestyle and eating habits with the severity of reflux esophagitis

Wang

2021

BMC Gastroenterol

View full text Add to dashboard Cite

Background The etiology of reflux esophagitis (RE) is multi-factorial. This study analyzed the relationship of depression, anxiety, lifestyle and eating habits with RE and its severity and further explored the impact of anxiety and depression on patients’ symptoms and quality of life. Methods From September 2016 to February 2018, a total of 689 subjects at Xuanwu Hospital Capital Medical University participated in this survey. They were divided into the RE group (patients diagnosed with RE on gastroscopy, n = 361) and the control group (healthy individuals without heartburn, regurgitation and other gastrointestinal symptoms, n = 328). The survey included general demographic information, lifestyle habits, eating habits, comorbidities, current medications, the gastroesophageal reflux disease (GERD) questionnaire (GerdQ), the Patient Health Questionnaire-9 depression scale and the General Anxiety Disorder-7 anxiety scale. Results The mean age and sex ratio of the two groups were similar. Multivariate logistic regression analysis identified the following factors as related to the onset of RE (p < 0.05): low education level; drinking strong tea; preferences for sweets, noodles and acidic foods; sleeping on a low pillow; overeating; a short interval between dinner and sleep; anxiety; depression; constipation; history of hypertension; and use of oral calcium channel blockers. Ordinal logistic regression analysis revealed a positive correlation between sleeping on a low pillow and RE severity (p = 0.025). Depression had a positive correlation with the severity of symptoms (rs = 0.375, p < 0.001) and patients’ quality of life (rs = 0.306, p < 0.001), whereas anxiety showed no such association. Conclusions Many lifestyle factors and eating habits were correlated with the onset of RE. Notably, sleeping on a low pillow was positively correlated with RE severity, and depression was positively related to the severity of symptoms and patients’ quality of life.

show abstract

“…A regular smoker was defined as a person who smoked ⩾1 cigarette/day, for 6 months continuously or cumulatively, in accordance with World Health Organization (WHO) standards [3] .A drinker was defined as a person with a daily alcohol consumption level of >25 g for men or >15 g for women, for 6 months continuously or cumulatively, in accordance with the recommendations of the Chinese Ministry of Health [3] .…”

Section: Definitionsmentioning

confidence: 99%

“…Preference was defined as engaging in the habit >3 days/week, continuously or cumulatively for 6 months [3] . In this study, preference for strong tea (>3 g of tea), spicy foods.…”

Section: Definitionsmentioning

confidence: 99%

“…The etiology of RE is multi-factorial. Lifestyle and eating habits such as smoking, drinking, preference for high-fat and fried foods, overeating are closely associated with RE [3][4][5][6] . In addition, it has been reported in the literature in recent years that mental disorders, especially anxiety and depression are closely related to the onset and prognosis of RE [7] , which seriously affect the quality of life of patients.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Study on the relationship of depression, anxiety, lifestyle and eating habits to the severity of reflux esophagitis

Wang

2020

Preprint

View full text Add to dashboard Cite

Background: The etiology of reflux esophagitis (RE) is multi-factorial. This study aims to analyze the risk factors of the RE, its severity and further explore the impact of anxiety and depression on the patients' symptoms and quality of life. Methods: From September 2016 to February 2018, a total of 689 subjects at Xuanwu Hospital Capital Medical University participated in the survey. They were divided into RE group (patients diagnosed as RE on gastroscopy, n = 361) and control group (healthy individuals without heartburn, regurgitation and other typical symptoms, n = 328). The survey included general demographic data, lifestyle habits, eating habits, GERD questionnaire (GerdQ), PHQ-9 depression scale and GAD-7 anxiety scale. Results: The mean age and sex ratio of the two groups were similar. Multivariate logistic regression analysis showed that low education level, drinking strong tea, preference for sweets and acidic foods, overeating, short interval between dinner and sleep, anxiety, depression, sleeping on low pillow and constipation were independent risk factors for RE (p< 0.05). Ordinal logistic regression analysis showed positive correlation between sleeping on low pillow and the severity of RE (p=0.024). Depression had positive correlation with the severity of symptoms (rs=0.375，P<0.001) and the quality of life (rs=0.306，P<0.001), whereas anxiety had no such association. Conclusions: Many lifestyle and eating habits are independent risk factors for the development of RE. Sleeping on low pillow was positively correlated with the severity of RE. Depression was positively related to the severity of symptoms and the quality of life.

show abstract

Lifestyle intervention for gastroesophageal reflux disease: a national multicenter survey of lifestyle factor effects on gastroesophageal reflux disease in China

Cited by 37 publications

References 39 publications

Smoking history and its relationship with comorbidities in patients with obstructive sleep apnea

Smoking history and its relationship with comorbidities in patients with obstructive sleep apnea

Study on the relationship of depression, anxiety, lifestyle and eating habits with the severity of reflux esophagitis

Study on the relationship of depression, anxiety, lifestyle and eating habits to the severity of reflux esophagitis

Contact Info

Product

Resources

About