Lifestyle in urology: Cancer

Sacco, Emilio; Vaccarella, L.; Bientinesi, Riccardo; Gandi, Carlo

doi:10.1177/0391560319846012

Cited by 12 publications

(5 citation statements)

References 130 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prostate cancer, the third most common type of cancer, is not directly correlated with tobacco smoking [ 20 ], but tobacco smokers have poorer survival and recurrence-free rates after prostate cancer diagnosis [ 21 ]. Bladder cancer, on the other hand, is known to be caused by tobacco smoking [ 20 ]. In a meta-analysis including 107 studies on bladder cancer, the RR for all smokers was 2.58 and even reached 3.47 for current smokers [ 22 ].…”

Section: Smoking-induced Diseasesmentioning

confidence: 99%

Smoking and Neuropsychiatric Disease—Associations and Underlying Mechanisms

Hahad

Daiber

Michal

et al. 2021

IJMS

View full text Add to dashboard Cite

Despite extensive efforts to combat cigarette smoking/tobacco use, it still remains a leading cause of global morbidity and mortality, killing more than eight million people each year. While tobacco smoking is a major risk factor for non-communicable diseases related to the four main groups—cardiovascular disease, cancer, chronic lung disease, and diabetes—its impact on neuropsychiatric risk is rather elusive. The aim of this review article is to emphasize the importance of smoking as a potential risk factor for neuropsychiatric disease and to identify central pathophysiological mechanisms that may contribute to this relationship. There is strong evidence from epidemiological and experimental studies indicating that smoking may increase the risk of various neuropsychiatric diseases, such as dementia/cognitive decline, schizophrenia/psychosis, depression, anxiety disorder, and suicidal behavior induced by structural and functional alterations of the central nervous system, mainly centered on inflammatory and oxidative stress pathways. From a public health perspective, preventive measures and policies designed to counteract the global epidemic of smoking should necessarily include warnings and actions that address the risk of neuropsychiatric disease.

show abstract

Section: Smoking-induced Diseasesmentioning

confidence: 99%

Smoking and Neuropsychiatric Disease—Associations and Underlying Mechanisms

Hahad

Daiber

Michal

et al. 2021

IJMS

View full text Add to dashboard Cite

show abstract

“…Kidney and bladder cancers had a higher incidence rate in rural areas, while prostate cancers were higher in metro areas 11 . Some lifestyle habits, such as smoking, physical activity, nutrition, sexual activity and personal hygiene, are modifiable factors influencing the development and progression of urological cancers 12 . In GLOBOCAN 2020, Bangladesh shows prostate cancer ranks 17, bladder cancer 18, kidney cancer 20, ca-penis 27 and testicular cancer 30 th position.…”

Section: Discussionmentioning

confidence: 99%

Current trends in the incidence of Urological malignancy at a tertiary level hospital in the northern part of Bangladesh

Arefin,

Bari,

Islam

et al. 2023

Bang J Urology

View full text Add to dashboard Cite

The second most common cause of death is malignancy. In clinical practice, genitourinary tumours are commonly encountered. Urological malignancies are raising due to increasing tobacco consumption, air and water pollution (arsenic, nitrate, chlorinated hydrocarbon) by unbalanced development, unhealthy diet, chronic infection, uncontrolled pesticides & fungicides used, food adulteration, using Chinese herbal products containing aristolochic acid, obesity and longer life expectancy. Over the past few years, advancement of diagnostic imaging, surgical technique, radiotherapy, chemotherapeutics and targeted agents have helped improve treatment outcomes. The incidence of urological malignancies is increasing like other malignancies in Bangladesh, which is poorly addressed. There is generally poor documentation of urological malignancies in Bangladesh. This study was carried out to document the pattern and distribution of urological malignancies in Rajshahi Medical College, Rajshahi, Bangladesh. Bangladesh J. Urol. 2022; 25(2): 98-105

show abstract

“…Amongst urological cancers, bladder cancer is the most common in the male urinary tract, displaying two to six times elevated frequency in male than female patients [ 2 ] and recording 440,864 cases and 158,785 deaths in male patients during 2020, according to Global Cancer Observatory [ 1 ]. Approximately 90–95% of bladder cancer cases are attributed to transformation of urothelial cells, lining throughout the urinary tract, in to cancer cells leading to urothelial carcinomas whereas squamous cell carcinoma, originating from bladder-lining cells, as well as adenocarcinoma [ 3 ] deriving from glandular cells account for ~4 and 2% of cases, respectively.…”

Section: Introductionmentioning

confidence: 99%

Accurate Characterization of Bladder Cancer Cells with Intraoperative Flow Cytometry

Paliouras

Μαρκόπουλος

Tsampalas

et al. 2022

Cancers

View full text Add to dashboard Cite

Bladder cancer represents a major health issue. Transurethral resection is the first line treatment and an accurate assessment of tumor margins might warrant complete tumor removal. Genomic instability and proliferative potential are common hallmarks of cancer cells. We have previously demonstrated the utility of intraoperative flow cytometry (iFC), a next-generation margin evaluation methodology for assessment of DNA content, in the detection of several types of malignancy. In the current study we investigated the possible value of iFC in the characterization of bladder cancer during surgery. Samples from a population of 52 people with urothelial cancer were included in the study. The total time for iFC evaluation is 3–5 min per sample and included a two-step analysis, including DNA-index and Tumor-index calculation. First, DNA-index calculation revealed 24 hyperploid and one hypoploid tumor. Second, cell cycle analysis and Tumor-index calculation revealed that tumor samples are distinguished from normal cells based on their significantly higher proliferative potential. The standard for iFC evaluation was pathology assessment and revealed that our protocol exhibits an accuracy of 98% in defining the presence of cancer cells in a given sample. Our results support the further assessment of iFC value towards its use as a novel malignancy evaluation tool in transurethral resections.

show abstract

Lifestyle in urology: Cancer

Cited by 12 publications

References 130 publications

Smoking and Neuropsychiatric Disease—Associations and Underlying Mechanisms

Smoking and Neuropsychiatric Disease—Associations and Underlying Mechanisms

Current trends in the incidence of Urological malignancy at a tertiary level hospital in the northern part of Bangladesh

Accurate Characterization of Bladder Cancer Cells with Intraoperative Flow Cytometry

Contact Info

Product

Resources

About