Lifestyle elements and risk of metabolic syndrome in adults

Abstract

Background The aim of the study was to investigate which elements of lifestyle are associated with metabolic health in adults, defined as the absence of components of metabolic syndrome (MetS) based on the International Diabetes Federation criteria. Methods Data from 10,277 individuals aged 40–65 years constituted the material of this study. Univariate and multivariate analyses with backward stepwise selection were carried out to identify the factors associated with the absence of metabolic disorders. Results No family history of cardiovascular disease increased the odds of being metabolically healthy 1.5-2-fold. Furthermore, the following factors were associated with higher odds of being metabolically healthy in men: abstinence from alcohol (healthy individuals vs. those with ≥3 [OR = 5.49 (2.23–13.52); p<0.001], ≥2 [OR = 4.52 (1.87–10.91); p = 0.001], and ≥1 components of MetS [OR = 3.04 (1.41–6.56); p = 0.005]), moderate alcohol use (healthy individuals vs. those with ≥3 [OR = 3.36 (1.54–7.32); p = 0.002], ≥2 [OR = 3.28 (1.52–7.10); p = 0.002], and ≥1 components of MetS [OR = 3.93 (1.64–9.42); p = 0.002]), moderate-to-vigorous physical activity (MVPA) >2 hours/day and sitting time of 3–6 hours/day. Drinking >2 cups of coffee per day (healthy vs. those with ≥3 [OR = 2.00 (1.47–2.71)], ≥2 [OR = 1.84 (1.38–2.45)], and ≥1 components of MetS [OR = 1.72 (1.30–2.28); all p<0.001]), limiting animal fats to <2 servings/day, MVPA >2 hours/day, and 7–8 hours of sleep per day were associated with higher odds of being metabolically healthy in women. Conclusions A healthy lifestyle increased the odds of being metabolically healthy. Some lifestyle modifications may appear effective in prevention of not only MetS, but also single metabolic risk factors.

Effect of Managing Metabolic Syndrome on Reversing Selected Determinants among Patients with Metabolic Syndrome

“…This may be related to the fact of , the longer the sleep hours the lower energy expenditure as spending less time doing physical activity, which increases the risk of obesity and MetS . In the same lineSuliga et al, (2022) mentioned a significant negative relation between spending moderate to vigorous activity >2 hours/day and sit 3-6 hours/day, walking and the number of MetS components.…”

“…It was designed by researchers rely on reviewed related literature (Suliga et al, 2022) to assess the biodemographic data of the studied patients. It included age, sex, educational level, job nature, disease onset, the numbers of smoked cigarettes / day, and family history.…”

The Metabolic Syndrome, a Human Disease

“…Both paths and effects have been found to be shared by MS and senescence [52,53]. (f) The effect of diet and lifestyle on MS emergence and development: closely related to type 2 diabetes and obesity (and the coordinated, and derived, cloud of disorders constituting MS) [54][55][56][57].…”

In Silico Discovery of Green Tea and Green Coffee Bioactive Compounds Against IGF-1R, PPAR-α, and TLR4 as a Therapeutic Candidate for Metabolic Disorder

“…Metabolic syndrome (MetS) is a constellation of interrelated risk factors, including abdominal obesity, hypertension, dyslipidemia, and elevated fasting blood glucose, collectively amplifying cardiovascular disease risk and T2DM. 1 T2DM is a chronic metabolic disorder with high blood sugar (glucose) levels. 2 MetS and T2DM are potentially life-altering medical conditions affecting millions worldwide and substantially burdening healthcare systems due to their profound implications for public health.…”