Lifestyle and preventive medical epigenetics

Sanusi, Kamaldeen Olalekan; Uthman, Yaaqub Abiodun; Ooi, Der Jiun; Ismail, Maznah; Imam, Mustapha Umar

doi:10.1016/b978-0-12-823928-5.00024-4

Cited by 3 publications

(1 citation statement)

References 170 publications

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“…Epigenetic changes can occur in response to a variety of environmental and lifestyle factors, such as diet, physical activity, and exposure to toxins. These changes can be transmitted from one generation to the next, and may play a key role in the development and progression of chronic diseases, including T2D [33].…”

Section: The Concept Of Epigenetics and Its Role In Chronic Diseasesmentioning

confidence: 99%

Preventive Epigenetic Mechanisms of Functional Foods for Type 2 Diabetes

et al. 2023

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Type 2 diabetes (T2D) is a growing global health problem that requires new and effective prevention and management strategies. Recent research has highlighted the role of epigenetic changes in the development and progression of T2D, and the potential of functional foods as a complementary therapy for the disease. This review aims to provide an overview of the current state of knowledge on the preventive epigenetic mechanisms of functional foods in T2D. We provide background information on T2D and its current treatment approaches, an explanation of the concept of epigenetics, and an overview of the different functional foods with demonstrated preventive epigenetic effects in T2D. We also discuss the epigenetic mechanisms by which these functional foods prevent or manage T2D, and the studies that have investigated their preventive epigenetic effects. In addition, we revisit works on the beneficial influence of functional foods against the programming and complications of parentally-triggered offspring diabetes. We also suggest, albeit based on scarce data, that epigenetic inheritance mechanistically mediates the impacts of functional nutrition against the metabolic risk of diabetes in offspring. Finally, our review highlights the importance of considering the preventive epigenetic mechanisms of functional foods as a potential avenue for the development of new prevention and management strategies for T2D.

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Section: The Concept Of Epigenetics and Its Role In Chronic Diseasesmentioning

confidence: 99%

Preventive Epigenetic Mechanisms of Functional Foods for Type 2 Diabetes

et al. 2023

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Transgenerational impact of maternal zinc deficiency on offspring metabolic outcomes in Drosophila melanogaster

Sanusi,

Abubakar,

Ibrahim

et al. 2024

The Journal of Nutritional Biochemistry

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Preventive Epigenetic Mechanisms of Functional Foods for Type 2 Diabetes

Abubakar¹,

Usman²,

Sanusi³

et al. 2023

Preprint

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Type 2 Diabetes (T2D) is a growing global health problem that requires new and effective prevention and management strategies. Recent research has highlighted the role of epigenetic changes in the development and progression of T2D, and the potential of functional foods as complementary therapy for the disease. This review aims to provide an overview of the current state of knowledge on the preventive epigenetic mechanisms of functional foods in T2D. We provide background information on T2D and its current treatment approaches, an explanation of the concept of epigenetics, and an overview of the different functional foods with demonstrated preventive epigenetic effects in T2D. We also discuss the epigenetic mechanisms by which these functional foods prevent or manage T2D and the studies that have investigated their preventive epigenetic effects. In addition, we revisit works on the beneficial influence of functional foods against the programming and complications of parentally-triggered offspring diabetes. We also postulate, albeit based on the scarce data, that epigenetic inheritance mechanistically mediates the impacts of functional nutrition against the metabolic risk of diabetes in the offspring. Finally, our review highlights the importance of considering the preventive epigenetic mechanisms of functional foods as a potential avenue for the development of new prevention and management strategies for T2D.

show abstract

Lifestyle and preventive medical epigenetics

Cited by 3 publications

References 170 publications

Preventive Epigenetic Mechanisms of Functional Foods for Type 2 Diabetes

Preventive Epigenetic Mechanisms of Functional Foods for Type 2 Diabetes

Transgenerational impact of maternal zinc deficiency on offspring metabolic outcomes in Drosophila melanogaster

Preventive Epigenetic Mechanisms of Functional Foods for Type 2 Diabetes

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