Lifestyle and cardiometabolic risk factors in the ethnic and non-ethnic population &gt; 15 years of age: results from the National Chilean Health Survey 2016-2017

Delgado‐Floody, Pedro; Lepin, Cristian Gabriel Álvarez; Ramírez, Rodrigo; Miranda‐Fuentes, Claudia; Saavedra, Paulina Ibacache; Campos, Christian T.; Cristi-Montero, Carlos; Sotomayor, Edgardo Molina; Caparrós, Cristian

doi:10.20960/nh.04252

Cited by 3 publications

(3 citation statements)

References 31 publications

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“…Both outcomes were measured with 8 h of fasting state and were measured similarly as reported in previous studies. (19) For blood pressure control, both systolic (SBP) and diastolic (DBP) were measured in the left arm three times and the average of these was registered. To the present study, there was used the current blood pressure categorization of the American Heart Association 2018; 'Normal BP' was defined as SBP/DBP less than 120/80 mmHg, 'elevated BP' (Ele) as SBP/DBP between 120-129/80 mmHg, 'stage 1 HTN' as SBP/DBP between 130-139/80-89 mmHg, and 'stage 2 HTN' as SBP/DBP greater than or equal to 140/90 mmHg.…”

Section: Diabetes and Arterial Hypertension Markers (Main Outcomes)mentioning

confidence: 99%

Muscleness and fatness phenotypes for diabetes and hypertension prediction from the Chilean National Health Survey 2016-17

Alvarez,

Caparros-Manosalva,

Muñoz-Mendoza

et al. 2024

Salud, Ciencia y Tecnología

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Introduction: Diabetes and arterial hypertension are increasing in adults, where calf circumference and waist circumference are two clinical epidemiological markers poorly studied for predicting cardiometabolic risk. Objective: To characterize four phenotypical models in the Chilean adult population based on muscleness and fatness using both calf circumference and waist circumference outcomes. Methodology: An epidemiological observational cross-sectional representative study based on the Chilean National Health Survey 2016-17, where four phenotypes groups were analyzed; Low skeletal muscle mass and high-waist circumference (Lsmm-Hwc, n=140), low skeletal muscle mass and low waist circumference (Lsmm-Lwc, n=242), high skeletal muscle mass and high waist circumference (Hsmm-Hwc, n=1076), and high skeletal muscle mass and low waist circumference (Hsmm-Lwc, n=1358). These groups described information about diabetes, hypertension prevalence, including other risk factors. Results: The reference group Hsmm-Lwc group showed lower fasting plasma glucose (FPG) vs. Hsmm-Hwc (90.4 [95%CI] [89.0; 91.8] vs. 111.7 [109.1; 114.3]), and vs. Lsmm-Hwc (90.4 [89.0; 91.8] vs. 118.3 [107.2; 129.4] mg/dL, both P<0.0001). Lower levels (i.e., appropriate) of FPG (R2 4.8%), glycated hemoglobin (R2 2.6%), systolic BP (R2 19.0%), and diastolic BP (R2 2.5%) were significantly associated (all, P<0.0001) with the Reference group Hsmm-Lwc. Conclusion: A high muscleness and low fatness phenotype is present in those who are younger adults, is associated with better glucose/blood pressure control, and reports low cardiovascular risk factors for diabetes and hypertension in Chilean adults.

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Section: Diabetes and Arterial Hypertension Markers (Main Outcomes)mentioning

confidence: 99%

Muscleness and fatness phenotypes for diabetes and hypertension prediction from the Chilean National Health Survey 2016-17

Alvarez,

Caparros-Manosalva,

Muñoz-Mendoza

et al. 2024

Salud, Ciencia y Tecnología

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“…To determine diabetes risk, FPG and glycated hemoglobin (HbA1c) were measured in fasting conditions (i.e., 8 h) by professional nurses, similar to a previous study [16]. Additionally, we reported the diabetes risk, using the question "diabetes suspects in fasting state" with categorical answers 'Yes' or 'No', which was included in the NHS16-17, where odds ratios (ORs) were reported (see statistical analysis section below).…”

Section: Diabetes and Arterial Hypertension Markers (Main Outcomes)mentioning

confidence: 99%

“…To determine sleep time, the following categorization was used similar to a previous study: <7 h/day, from 7 to 9 h/day, and >9 h/day to denote low, middle, and high levels of sleep time, respectively [16].…”

Section: Secondary Cardiometabolic Risk Factors (Secondary Outcomes)mentioning

confidence: 99%

A Higher Skeletal Muscle Mass and Lower Adiposity Phenotype Is Associated with Better Cardiometabolic Control in Adults with Hip and Knee Osteoarthritis: Results from the Chilean National Health Survey 2016–2017

Guede-Rojas,

Ibacache-Saavedra,

Leal

et al. 2023

Nutrients

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Objective: This study aimed to (1) characterize cardiometabolic factors in self-reported hip and knee osteoarthritis (OAD) across four body composition phenotypes defined by muscle mass and adiposity, and (2) associate risk factors with diabetes and hypertension (HTN). Methods: A cross-sectional analysis of the Chilean National Health Survey 2016–17 (n = 4996) stratified participants into four groups: low skeletal muscle mass/high waist circumference (Low-SMM/High-WC), low SMM/low WC (Low-SMM/Low-WC), high SMM/high WC (High-SMM/High-WC), and high SMM/low WC (reference group). Each group was further divided into subgroups with or without diagnosed hip or knee OAD. The main outcomes were fasting plasma glucose, systolic (SBP)/diastolic (DBP) blood pressure (continuous outcomes), and other secondary factors such as cardiovascular risk (CVR). Results: In the hip OAD subgroup, the Low-SMM/High-WC groups had significantly higher SBP versus the reference value (145 vs. 127 mmHg, p < 0.0001, diff +18 mmHg). In the knee OAD subgroup, the Low-SMM/High-WC groups had significantly higher SBP versus the reference value (141 vs. 134 mmHg, p < 0.0001, diff +7 mmHg). The SBP showed a significant interaction between the group and OAD diagnosis (p = 0.007 hip OAD; p < 0.0001 knee OAD). Conclusions: Hip and knee OAD associates with elevated SBP/DBP in older adults. OAD groups showed an OR above 2 for diabetes, 2.7 for HTN, 4.5 for metabolic syndrome, and over 2 for moderate-to-high cardiovascular risk. OAD interacts substantially with cardiometabolic factors, especially in low muscle mass/high adiposity phenotypes. Lifestyle optimization of physical activity and nutrition to preserve muscle mass and mitigate adiposity is essential for cardiometabolic health promotion in OAD patients.

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Obesity Is Associated with Changes in Laboratory Biomarkers in Chilean Patients Hospitalized with COVID-19

Viscardi

Marileo

Delgado

et al. 2023

JCM

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Background and aims: It is reported that patients with obesity are more frequently hospitalized for COVID-19, and evidence exists that obesity is a risk factor, regardless of other comorbidities. The objective of this study was to evaluate the association of obesity with changes in laboratory biomarkers in hospitalized Chilean patients. Materials and methods: A total of 202 hospitalized patients (71 with obesity and 131 without obesity) with a diagnosis of COVID-19 were included in the study. Demographic, clinical, and laboratory (days 1, 3, 7, 15) data were obtained. We performed a statistical analysis, assuming significance with a value of p < 0.05. Results: Significant differences in chronic respiratory pathology are observed between patients with and without obesity. The inflammatory markers CPR, ferritin, NLR, and PLR are elevated during the evaluated period, while changes in leukocyte populations are present on day 1 (eosinophils) and day 3 (lymphocytes). Finally, a persistent elevation of D-dimer level is observed, presenting significant differences on day 7 between patients with and without obesity. Obesity had a positive correlation with admission to the critical patient unit, invasive mechanical ventilation, and length of hospital stay. Conclusion: Patients with obesity hospitalized for COVID-19 present marked elevations of inflammatory and hemostasis parameters, with a correlation between obesity, changes in laboratory biomarkers, and the risk of adverse clinical outcomes also observed.

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Lifestyle and cardiometabolic risk factors in the ethnic and non-ethnic population > 15 years of age: results from the National Chilean Health Survey 2016-2017

Cited by 3 publications

References 31 publications

Muscleness and fatness phenotypes for diabetes and hypertension prediction from the Chilean National Health Survey 2016-17

Muscleness and fatness phenotypes for diabetes and hypertension prediction from the Chilean National Health Survey 2016-17

A Higher Skeletal Muscle Mass and Lower Adiposity Phenotype Is Associated with Better Cardiometabolic Control in Adults with Hip and Knee Osteoarthritis: Results from the Chilean National Health Survey 2016–2017

Obesity Is Associated with Changes in Laboratory Biomarkers in Chilean Patients Hospitalized with COVID-19

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