Life-Threatening Intratumoral Hemorrhage in an Infant with Hepatoblastoma Successfully Treated with Hepatic Arterial Embolization

Ronsley, Rebecca; Cardarelli-Leite, Leandro; Burrill, Joshua; Deyell, Rebecca J.; Heran, Manraj K.S.

doi:10.1016/j.jvir.2021.04.007

Cited by 4 publications

(3 citation statements)

References 2 publications

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“…First, these tumors are generally large and symptomatic besides symptoms associated with bleeding, including pain, early satiety, respiratory distress and obstructive symptoms mandating tumor excision. Second, surgical excision of GIST is considered curative, and adjacent organ involvement is generally rare making the excision relatively a safe and effective endeavor [ 10 , 11 ]. On the other hand, surgical exploration comes with the risk of tumor rupture and consequent hemorrhage, tumor recurrence and shortened survival [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Giant gastric GIST with fast-growing mass after intra-tumoral bleeding

Duguma,

Seid,

Shumiye

et al. 2023

Journal of Surgical Case Reports

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Only a few instances of giant gastrointestinal stromal tumors and even fewer cases of such tumors with intra-tumoral bleeding have ever been reported. This report represents a case with both giant size and intra-tumoral spontaneous hemorrhage. Here a 42-year-old male patient presented with abdominal pain and abdominal distention of 5-month duration. The distention had fast growth over 1 month before the hospital presentation. Physical examination showed a conjunctival pallor and an ill-defined abdominal mass. A contrast-enhanced computed tomography (CT) scan showed a huge intra-abdominal mass with variable enhancements. Surgical exploration was done and a huge mass measuring 10.5 kg with dimensions of 32 × 30 × 15 cm was excised en-bloc with distal gastrectomy.

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Section: Discussionmentioning

confidence: 99%

Giant gastric GIST with fast-growing mass after intra-tumoral bleeding

Duguma,

Seid,

Shumiye

et al. 2023

Journal of Surgical Case Reports

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“…2 Two recent case reports described the successful use of TAE in controlling life-threatening intra-abdominal bleeding associated with hepatoblastoma in a 2-year-old and a 3-month-old child, respectively. 9,10 Embosphere and gelfoam slurry were used in the first case and gelfoam slurry alone was used in the second case. EG gel S plus, a type of calibrated gelfoam particles packaged in pre-filled syringe, was used as an embolic agent in our series.…”

Section: Discussionmentioning

confidence: 99%

“…The resectability of ruptured hepatoblastoma of higher stages (i.e., PRETEXT II and III) would be dependent on the tumor involvement and surgical expertise 2 . Two recent case reports described the successful use of TAE in controlling life‐threatening intra‐abdominal bleeding associated with hepatoblastoma in a 2‐year‐old and a 3‐month‐old child, respectively 9,10 . Embosphere and gelfoam slurry were used in the first case and gelfoam slurry alone was used in the second case.…”

Section: Discussionmentioning

confidence: 99%

Management of acute intra‐abdominal hemorrhage in ruptured hepatoblastoma with transarterial embolization using calibrated gelfoam particles

Fung

Liu

Chung

et al. 2022

Pediatric Blood & Cancer

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This brief report aims to evaluate the treatment outcome of transarterial embolization in ruptured hepatoblastoma complicated with acute intra‐abdominal hemorrhage. Three children (mean age 6 years) with high‐risk hepatoblastoma presented with rupture and acute intra‐abdominal hemorrhage. In addition to aggressive fluid resuscitation and blood product support, super‐selective embolization of the arteries with active bleeding or pseudoaneurysm was performed using calibrated gelfoam particles, with a technical success rate of 100%. Hemodynamic status and hemoglobin level were normalized in all patients within 2 days postembolization. The 30‐day survival rate was 100%. No major complication was detected apart from mild elevation of alanine transaminase.

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