1981
DOI: 10.1016/s0140-6736(81)92567-8
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Life Events and Appendicectomy

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Cited by 85 publications
(22 citation statements)
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“…17 The presence of pain in the right iliac fossa without evidence of organic disease is a common phenomenon and may result in the removal of a normal appendix or the diagnosis of 'grumbling appendix'. '8 19 The observation that pain, localised to other sites in the abdomen, is temporally related to the entry of food into the colon, is in keeping with the results of balloon distension of the colon, which can induce pain at sites which do not necessarily correspond to the anatomical source. 20 Patients with irritable bowel syndrome exhibit a greater degree of life stress than normal subjects,2' and experimental stress dramatically influences colonic motor activity.…”
Section: Discussionmentioning
confidence: 79%
“…17 The presence of pain in the right iliac fossa without evidence of organic disease is a common phenomenon and may result in the removal of a normal appendix or the diagnosis of 'grumbling appendix'. '8 19 The observation that pain, localised to other sites in the abdomen, is temporally related to the entry of food into the colon, is in keeping with the results of balloon distension of the colon, which can induce pain at sites which do not necessarily correspond to the anatomical source. 20 Patients with irritable bowel syndrome exhibit a greater degree of life stress than normal subjects,2' and experimental stress dramatically influences colonic motor activity.…”
Section: Discussionmentioning
confidence: 79%
“…44 A precipitating factor is the proverbial "straw that breaks the camel's back," setting off an acute episode of MUPS and related morbidity. Factors that precipitate MUPS include biologic stressors, 45,46 psychosocial stressors, [47][48][49] acute psychiatric disorders, 50 and epidemic health concerns. [51][52][53][54] Perpetuating factors are those that maintain, exacerbate, or prolong symptoms, distress, and disability after they occur.…”
Section: Common Determinants Of Natural Historymentioning
confidence: 99%
“…More recently, Creed [31] has put for ward that a stressful life, including emotional problems and depression, may be influential. As to precipitating causes.…”
Section: Predisposition and Causationmentioning
confidence: 99%