Lidocaine for preventing postoperative sore throat

Tanaka, Yuu; Nakayama, Takeo; Nishimori, Mina; Sato, Yuki; Furuya, Hitoshi

doi:10.1002/14651858.cd004081.pub2

Cited by 49 publications

(46 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…20 Lidocaine has also been used to break post-extubation stridor and laryngospasm in adult patients 19,21 and to decrease postoperative sore throat after extubation. 22 Although most of these studies refer to adult patients, the present results in pediatric patients are consistent with these findings. Even though lidocaine is a relatively short-acting local anesthetic, we could show an effect of local application on the postoperative and overall complication rate.…”

Section: Discussionsupporting

confidence: 90%

Topical lidocaine reduces the risk of perioperative airway complications in children with upper respiratory tract infections

Schebesta

Güloglu

Chiari

et al. 2010

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

Purpose To determine the effect of topically applied lidocaine on perioperative airway complications when using a laryngeal mask airway device (LMAD) in children either with or without a history of recent or ongoing upper respiratory tract infection (URI). Methods In a randomized controlled double-blind trial, 34 children with a history of recent or ongoing URI and 32 non-URI children-all of whom were younger than age ten and scheduled to undergo minor surgical procedureswere randomly assigned to either a lidocaine or a placebo group. In the lidocaine group, an LMAD was lubricated with lidocaine gel before insertion, and a clear lubricating gel was used in the placebo group. The following data were recorded after standardized anesthesia induction and airway management: postoperative complications, such as coughing, desaturation, laryngospasm, and increased oral secretions, as well as length of stay in the postanesthetic recovery unit. Results Children with URI had a lower overall perioperative complication rate if they received a lidocaine gel (35%) rather than placebo (94%) (P \ 0.01). Also, the incidence of postoperative coughing was less (12% vs 53%; P = 0.03). In non-URI patients, lidocaine did not significantly reduce the rate of airway complications compared with placebo (17% vs 24%, respectively).Conclusion Lubrication of the LMAD with lidocaine gel reduces the incidence of airway complications in children with an upper respiratory tract infection. RésuméObjectif De´terminer l'effet d'une application topique de lidocaı¨ne sur les complications pe´riope´ratoires au niveau des voies ae´riennes lors de l'utilisation d'un masque larynge( LMAD) chez des enfants avec ou sans infection re´cente ou actuelle des voies respiratoires supe´rieures. Méthode Dans une e´tude randomise´e contrôle´e à double insu, 34 enfants avec une infection re´cente ou actuelle des voies respiratoires supe´rieures et 32 enfants sans infection, tous plus jeunes que 10 ans et devant subir des interventions chirurgicales mineures, ont e´te´randomise´s a`recevoir soit de la lidocaı¨ne, soit un placebo. Dans le groupe lidocaı¨ne, un LMAD a e´te´lubrifie´a`l'aide de lidocaı¨ne en gel avant l'insertion, et un gel lubrifiant clair a e´te´utilise´dans le groupe placebo. Les donne´es suivantes ont e´te´enregistre´es apre`s une induction de l'anesthe´sie et une prise en charge standard des voies ae´riennes: les complications postope´ratoires, telles que toux, de´saturation, laryngospasme et se´cre´tions orales accrues, ainsi que la dure´e de se´jour dans la salle de re´veil post-anesthe´sique. Résultats Les enfants souffrant d'infection des voies respiratoires supe´rieures ont montre´un taux global de complications pe´riope´ratoires plus bas lorsqu'ils ont reçu de la lidocaı¨ne en gel (35 %) plutôt que le placebo (94 %) (P\0,01). De plus, l'incidence de toux postope´ratoire e´tait moindre (12 % vs 53 %; P = 0,03). Chez les patients ne souffrant pas d'infection des voies respiratoires supe´rieures, la lidocaı¨ne n'a pas re´duit le taux de ...

show abstract

Section: Discussionsupporting

confidence: 90%

Topical lidocaine reduces the risk of perioperative airway complications in children with upper respiratory tract infections

Schebesta

Güloglu

Chiari

et al. 2010

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

show abstract

“…As shown in table 2, the severity of post-intubation sore throat was significantly reduced in patients receiving tetracaine as inflation medium, compared with patients receiving other inflation media (P<0.05), at 6 (primary outcome), 24 and 48 (secondary outcomes) hours after extubation. As previously reported (20), lidocaine, per se, could reduce sore throat when compared with normal saline or air (P<0.05).…”

Section: Resultssupporting

confidence: 82%

Effect of Intra-Cuff Tetracaine on Preventing Postoperative Sore Throat after Gynecological Surgery

Zhu¹,

Wu²,

Song³

et al. 2015

J Anesth Perioper Med

View full text Add to dashboard Cite

Background: Postoperative sore throat is one of the most common complications associated with endotracheal intubation. It has been reported that intra-cuff application of lidocaine could reduce its incidence and severity. In the present study, we would like to investigate the safety and efficacy of intra-cuff use of tetracaine, one of the most commonly used topical anesthetic, on prevention of postoperative sore throat. Methods: Female patients (age from 18-60 years) undergoing gynecological surgery under general anesthesia were included. Assigned randomly, the patients received one of the following cuff inflation media: air, 0.9% saline, 2% lidocaine or 1% tetracaine (N=25 in each group). The cuff was inflated with minimal occlusive volume technique. Intra-cuff pressure was measured with a manometer. The primary outcome was the severity of postoperative sore throat, assessed by visual analogue scale (VAS) at 6 hours after extubation. The secondary outcomes included the incidences of complications during emergence of anesthesia and extubation, such as tube intolerance, coughing, restlessness, hoarseness, and laryngospasm, as well as the VAS scores for sore throat at 24 and 48 hours after extubation. The safety and efficacy were further tested by pathological examination of tracheal mucosa after 4-hour intubation in animal study and measurement of diffused anesthetic via the cuff wall in in vitro study, respectively. Results: There was no difference in volume of inflation medium, or intra-cuff pressure between groups. Tetracaine significantly reduced the severity of postoperative sore throat during the 48-hour postoperative observation period, compared with lidocaine (P<0.05) or air (P<0.01). There were also fewer patients with tube intolerance, coughing, restlessness and hoarseness in tetracaine group, compared with lidocaine group (P<0.05) or air group (P<0.01). No abnormality was found in tracheal mucosa pathology and tetracaine diffused via the cuff wall continuously. Conclusions: Our study showed that inflating the cuff with tetraciane is safe and effective in preventing tube-induced emergence phenomena.

show abstract

“…It can also be due to the osmolarity of the jelly since mucosal irritation can depend on the osmolarity of the lubricant [18]. But some other studies have shown a better result with the use of lidocaine [19]. Our significant finding at 24 h may also be due to prolonged action of betamethasone gel while the effect of lidocaine wears off earlier, producing a wider gap in the incidence and severity score at 24 h.…”

Section: Discussionmentioning

confidence: 68%

Betamethasone gel compared with lidocaine jelly to reduce tracheal tube related postoperative airway symptoms: a randomized controlled trial

Thapa

Shrestha

Shrestha³

et al. 2017

BMC Res Notes

View full text Add to dashboard Cite

Background and objectives: Post-operative airway symptoms can be troublesome to patients following an uneventful general anesthesia with endotracheal intubation. In this study, we compared the effectiveness of lubricating an endotracheal tube with betamethasone gel or lidocaine jelly with using an unlubricated tube in reducing the incidence and severity of postoperative sore throat, hoarseness and cough.Methods: This was a prospective, randomized, single-blind comparative study carried out among 120 ASA I and II patients aged 18-65 years undergoing elective surgery under general anesthesia with endotracheal intubation. Patients were randomly divided into three groups of 40 patients each. Endotracheal tube used for patients in group C was unlubricated, while that for group B and group L were lubricated up to 15 cm mark with 2.5 ml of 0.05% betamethasone gel or 2% lidocaine jelly respectively. Incidence and severity of postoperative sore throat, hoarseness and cough were observed at 1, 6 and 24 h following extubation. Results:At 24 h following extubation, group B had the lowest incidence of postoperative sore throat among the three groups (group B: 12.5% vs group L: 37.5% vs group C: 25%; p = 0.036). Severity of postoperative sore throat at 24 h was less with betamethasone (score 0: 87.5%, 1: 10%) compared with lidocaine (score 0: 62.5%, 1: 37.5%) and control (score 0:75%, 1: 20%) (p = 0.006). Observations at other times and of other variables were comparable. Conclusion:Wide spread application of 0.05% betamethasone gel to lubricate the endotracheal tube significantly reduces the incidence and severity of sore throat at 24 h of extubation but not of hoarseness or cough.

show abstract

Lidocaine for preventing postoperative sore throat

Cited by 49 publications

References 31 publications

Topical lidocaine reduces the risk of perioperative airway complications in children with upper respiratory tract infections

Topical lidocaine reduces the risk of perioperative airway complications in children with upper respiratory tract infections

Effect of Intra-Cuff Tetracaine on Preventing Postoperative Sore Throat after Gynecological Surgery

Betamethasone gel compared with lidocaine jelly to reduce tracheal tube related postoperative airway symptoms: a randomized controlled trial

Contact Info

Product

Resources

About