Licht- und elektronenmikroskopische Untersuchungen am Plattenepithel des äußeren Gehörganges und des Trommelfelles bei tierexperimentell induzierten Cholesteatomen

Galić, M.; Heumann, H; Pohl, Donald R.; Steinbach, E.

doi:10.1055/s-2007-1008581

Laryngo-Rhino-Otol

1982

DOI: 10.1055/s-2007-1008581

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Licht- und elektronenmikroskopische Untersuchungen am Plattenepithel des äußeren Gehörganges und des Trommelfelles bei tierexperimentell induzierten Cholesteatomen

M. Galić¹,

H Heumann²,

Donald R. Pohl³

et al.

Abstract: Die Bedeutung der hinten oben gelegenen Gehorgangshaut für die Entstehung des Cholesteatoms ist von vielen Autoren aufgrund klinischer Beobachtungen und tierexperimenteller Untersuchungen herausgesteilt worden. Sic wurde durch Steinbach und Mitarbeiter besttigt, die bei Kanin

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The formation of ultrastructural epithelial and subepithelial connective tissue changes in experimentally induced cholesteatomas in guinea pigs

Galić

Heumann

Pohl

et al. 1985

Arch Otorhinolaryngol

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Histoacryl-induced cholesteatomas were produced in guinea pigs at the posterosuperior part of the external ear canal adjacent to the tympanic membrane. Semithin and ultrathin tissue sections were used to study primary formation of the cholesteatoma as well as the influence of the altered epithelium upon the bordering zone of connective tissue. Quantitative and qualitative tissue changes were analyzed by electron microscopy and showed degradation and new formation of collagen and activation of fibroblasts. Our findings are similar to those previously reported on human cholesteatomas and indicate that the bordering subepithelial tissue seems to be influenced through the basilar membrane.

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The formation of ultrastructural epithelial and subepithelial connective tissue changes in experimentally induced cholesteatomas in guinea pigs

Galić

Heumann

Pohl

et al. 1985

Arch Otorhinolaryngol

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Squamous Epithelium in the Middle Ear and Sinus

Tutkun

Batman²,

Üneri³

et al. 1994

Ear Nose Throat J

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This study has been performed between December 1990—March 1991 in the Microsurgery laboratory of the Marmara University Hospital. Twelve healthy albino guinea pigs were used as a study group while the control group consists of three animals. The potentials for cholesteatoma formation of the squamous epithelium, namely the squamous epithelium of the posterior superior part of the external ear canal skin and normal skin, were investigated. Among 24 subjects who were implanted by canal skin, cholesteatoma was fanned in 21 of them. Likewise, 19 of 24 animals implanted by normal skin came out with cholesteatoma formation. Between these two types of epithelium, there is no statistical difference in cholesteatoma formation (p >0.5).

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Licht- und elektronenmikroskopische Untersuchungen am Plattenepithel des äußeren Gehörganges und des Trommelfelles bei tierexperimentell induzierten Cholesteatomen

Abstract: Die Bedeutung der hinten oben gelegenen Gehorgangshaut für die Entstehung des Cholesteatoms ist von vielen Autoren aufgrund klinischer Beobachtungen und tierexperimenteller Untersuchungen herausgesteilt worden. Sic wurde durch Steinbach und Mitarbeiter besttigt, die bei Kanin

Cited by 2 publications

References 0 publications

The formation of ultrastructural epithelial and subepithelial connective tissue changes in experimentally induced cholesteatomas in guinea pigs

The formation of ultrastructural epithelial and subepithelial connective tissue changes in experimentally induced cholesteatomas in guinea pigs

Squamous Epithelium in the Middle Ear and Sinus

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